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- W2032024102 abstract "Helicobacter pylori seem to avoid areas of intestinal metaplasia in the gastric mucosa, but attachment of these bacteria to epithelium with the appearance of incomplete intestinal metaplasia has been documented. To characterize the nature of the epithelium to which H pylori was attached, we carried out an immunohistochemical study using monoclonal antibodies against gastric surface mucous cell mucins (Ml), blood group—related carbohydrates antigens (Lea, sialyl Lea, Leb, type 1H, and type 2H) and sialyl Tn antigen. The results of this study suggest that these areas of H pylori attachment represent a hybrid epithelium whose cells share characteristics of both gastric surface mucous cells and intestinal metaplastic cells. Whether all areas of incomplete intestinal metaplasia represent an intermediate stage between the normal gastric epithelium and the fully developed complete type of metaplasia remains to be determined." @default.
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- W2032024102 date "1998-08-01" @default.
- W2032024102 modified "2023-10-13" @default.
- W2032024102 title "Intestinal metaplasia with adherent Helicobacter pylori: A hybrid epithelium with both gastric and intestinal features" @default.
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- W2032024102 doi "https://doi.org/10.1016/s0046-8177(98)90455-5" @default.
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