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- W2032050655 abstract "Microvascular leakage of macromolecules was studied in the hamster cheek pouch preparation using fluorescein labelled dextran (FITC-dextran 145 Mw = 145,000) as a tracer. When the preparation is superfused with 10−5 M histamine or 10−7 M bradykinin the permeability to macromolecules increases exclusively at postcapillary venules. Microinjections of 30–200 picolitres (pl) of 0.1 M histamine and 10−4 M bradykinin close to arterioles and capillaries caused extravasation from several postcapillary venules at a distance from site of injection but not from arterioles or capillaries. The minimal diameter of the postcapillary venules where leakage occurred was (n = 45) 8.6 ± 2.6 (S.D.) μm and the maximal diameter was 14.0 ± 5.3 μm. Histamine and bradykinin caused leakage of macromolecules in postcapillary venules but not in arterioles, capillaries or larger venules even when these were exposed to high local concentrations of these agents." @default.
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- W2032050655 date "1979-01-01" @default.
- W2032050655 modified "2023-09-26" @default.
- W2032050655 title "Dimensions of Postcapillary Venules Sensitive to Bradykinin and Histamine-induced Leakage of Macromolecules" @default.
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- W2032050655 doi "https://doi.org/10.3109/03009737909179139" @default.
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