FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032051024> ?p ?o ?g. }

• W2032051024 endingPage "515" @default.
• W2032051024 startingPage "505" @default.
• W2032051024 abstract "Quantitative estimates of potential cancer risk associated with eating heterocyclic amines (HAs) in cooked foods and food products, known to be highly mutagenic in the Ames/Salmonella assay and to cause cancer in laboratory animals, rely on estimates of carcinogenic potency from animal bioassay data. New estimates of potential human cancer potency are presented for 10 HAs associated with potential human dietary exposure from cooked-food sources. These estimates differ from previous similar estimates in that they properly reflect the fact that most of these HAs exhibit a pronounced ability to induce tumours at multiple histologically distinct sites within each sex/species tested, and so might be expected to be multipotent carcinogens in humans as well. Thus, in addition to 82 tumour-type-specific potencies estimated for these compounds, 24 additional estimates of aggregate potency (to induce one or more tumour types) were made, using different methods to scale estimated bioassay cancer potency to humans. The currently unknown potency of an additional cooked-food HA was estimated using linear regressions of log-carcinogenic on log-mutagenic potency for the other 10 HAs, some of which were highly significant (e.g. r = 0.85, P < 0.004). The potency estimates obtained are consistent with an upper-bound cancer risk between 10−3 and 10−4 for an average lifetime cooked-beef intake of 3.3 g/kg/day (or approx. 0.5 lb/day). Use of these potency estimates to obtain more realistic upper-bound estimates of dietary-HA risk will require detailed HA-exposure assessments." @default.
• W2032051024 created "2016-06-24" @default.
• W2032051024 creator A5083843099 @default.
• W2032051024 date "1994-06-01" @default.
• W2032051024 modified "2023-10-03" @default.
• W2032051024 title "Cancer potencies of heterocyclic amines found in cooked foods" @default.
• W2032051024 cites W1970218284 @default.
• W2032051024 cites W1971495457 @default.
• W2032051024 cites W1972438565 @default.
• W2032051024 cites W1976191642 @default.
• W2032051024 cites W1977003892 @default.
• W2032051024 cites W1977262016 @default.
• W2032051024 cites W1979826300 @default.
• W2032051024 cites W1980496573 @default.
• W2032051024 cites W1984466882 @default.
• W2032051024 cites W1985642242 @default.
• W2032051024 cites W1988026736 @default.
• W2032051024 cites W1994665973 @default.
• W2032051024 cites W1995509223 @default.
• W2032051024 cites W1995834499 @default.
• W2032051024 cites W2000767438 @default.
• W2032051024 cites W2003078659 @default.
• W2032051024 cites W2012062618 @default.
• W2032051024 cites W2012814689 @default.
• W2032051024 cites W2025520735 @default.
• W2032051024 cites W2025613531 @default.
• W2032051024 cites W2035213967 @default.
• W2032051024 cites W2035342243 @default.
• W2032051024 cites W2036964953 @default.
• W2032051024 cites W2046172892 @default.
• W2032051024 cites W2050847528 @default.
• W2032051024 cites W2052974030 @default.
• W2032051024 cites W2056920355 @default.
• W2032051024 cites W2057797408 @default.
• W2032051024 cites W2059307512 @default.
• W2032051024 cites W2063171708 @default.
• W2032051024 cites W2076839675 @default.
• W2032051024 cites W2079929598 @default.
• W2032051024 cites W2091456769 @default.
• W2032051024 cites W2120141484 @default.
• W2032051024 cites W2124251966 @default.
• W2032051024 cites W2139234269 @default.
• W2032051024 cites W2141654351 @default.
• W2032051024 cites W2146297832 @default.
• W2032051024 cites W2313684247 @default.
• W2032051024 cites W2334212928 @default.
• W2032051024 cites W4244581832 @default.
• W2032051024 cites W4247806009 @default.
• W2032051024 doi "https://doi.org/10.1016/0278-6915(94)90106-6" @default.
• W2032051024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8045455" @default.
• W2032051024 hasPublicationYear "1994" @default.
• W2032051024 type Work @default.
• W2032051024 sameAs 2032051024 @default.
• W2032051024 citedByCount "37" @default.
• W2032051024 countsByYear W20320510242012 @default.
• W2032051024 countsByYear W20320510242013 @default.
• W2032051024 countsByYear W20320510242019 @default.
• W2032051024 crossrefType "journal-article" @default.
• W2032051024 hasAuthorship W2032051024A5083843099 @default.
• W2032051024 hasConcept C104488531 @default.
• W2032051024 hasConcept C114246631 @default.
• W2032051024 hasConcept C121608353 @default.
• W2032051024 hasConcept C126322002 @default.
• W2032051024 hasConcept C185592680 @default.
• W2032051024 hasConcept C18903297 @default.
• W2032051024 hasConcept C202751555 @default.
• W2032051024 hasConcept C31903555 @default.
• W2032051024 hasConcept C33070731 @default.
• W2032051024 hasConcept C55493867 @default.
• W2032051024 hasConcept C57992300 @default.
• W2032051024 hasConcept C71924100 @default.
• W2032051024 hasConcept C86803240 @default.
• W2032051024 hasConceptScore W2032051024C104488531 @default.
• W2032051024 hasConceptScore W2032051024C114246631 @default.
• W2032051024 hasConceptScore W2032051024C121608353 @default.
• W2032051024 hasConceptScore W2032051024C126322002 @default.
• W2032051024 hasConceptScore W2032051024C185592680 @default.
• W2032051024 hasConceptScore W2032051024C18903297 @default.
• W2032051024 hasConceptScore W2032051024C202751555 @default.
• W2032051024 hasConceptScore W2032051024C31903555 @default.
• W2032051024 hasConceptScore W2032051024C33070731 @default.
• W2032051024 hasConceptScore W2032051024C55493867 @default.
• W2032051024 hasConceptScore W2032051024C57992300 @default.
• W2032051024 hasConceptScore W2032051024C71924100 @default.
• W2032051024 hasConceptScore W2032051024C86803240 @default.
• W2032051024 hasIssue "6" @default.
• W2032051024 hasLocation W20320510241 @default.
• W2032051024 hasLocation W20320510242 @default.
• W2032051024 hasOpenAccess W2032051024 @default.
• W2032051024 hasPrimaryLocation W20320510241 @default.
• W2032051024 hasRelatedWork W1970521072 @default.
• W2032051024 hasRelatedWork W1984875201 @default.
• W2032051024 hasRelatedWork W1993356028 @default.
• W2032051024 hasRelatedWork W2010408227 @default.
• W2032051024 hasRelatedWork W2029790424 @default.
• W2032051024 hasRelatedWork W2040961261 @default.
• W2032051024 hasRelatedWork W2045752656 @default.
• W2032051024 hasRelatedWork W2140453635 @default.

• next