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- W2032053343 abstract "The use of computer simulation software for high-performance liquid chromatographic (HPLC) method development is considered. In particular, gradient elution data entered into DryLab G/plus are used to predict isocratic retention times. The motivation was to establish whether data generated in a research-grade, gradient environment might be used to simulate accurately isocratic HPLC conditions applicable to a process monitoring operation. Good agreement between experimentally obtained and computer-predicted retention times for a homologous series of alkylketones was found for the conversion from gradient to isocratic elution conditions." @default.
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- W2032053343 date "1991-01-01" @default.
- W2032053343 modified "2023-09-23" @default.
- W2032053343 title "Computer simulation of isocratic retentions of alkylketones using gradient data" @default.
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- W2032053343 doi "https://doi.org/10.1016/s0021-9673(01)88532-0" @default.
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