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• W2032062835 abstract "A scaffold harboring the desired features such as biodegradation, biocompatibility, porous structure could serve as template for bone tissue engineering. In the present study, chitosan (CS), nano-scaled silicon dioxide (Si) and zirconia (Zr) were combined by freeze drying technique to fabricate a bio-composite scaffold. The bio-composite scaffold (CS/Si/Zr) was characterized by SEM, XRD and FT-IR studies. The scaffold possessed a porous nature with pore dimensions suitable for cell infiltration and colonization. The presence of zirconia in the CS/Si/Zr scaffold decreased swelling and increased biodegradation, protein adsorption and bio-mineralization properties. The CS/Si/Zr scaffold was also found to be non-toxic to rat osteoprogenitor cells. Thus, we suggest that CS/Si/Zr bio-composite scaffold is a potential candidate to be used for bone tissue engineering." @default.
• W2032062835 created "2016-06-24" @default.
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• W2032062835 date "2011-12-01" @default.
• W2032062835 modified "2023-10-17" @default.
• W2032062835 title "Chitosan scaffolds containing silicon dioxide and zirconia nano particles for bone tissue engineering" @default.
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• W2032062835 doi "https://doi.org/10.1016/j.ijbiomac.2011.09.016" @default.
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