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- W2032083415 abstract "To observe the antihypertensive efficacy and safety of Valsartan combined with Hydrochorothatizide. 151 hypertensive patients were divided into three groups: Valsartan group, Valsartan and Hydrochorothatizide group, Hydrochorothatizide group, which were treated with valsartan, Valsartan and Hydrochorothatizide, Hydrochorothatizide for 4 weeks respectively. Clinical blood pressure, ambulatory blood pressure and biochemical data were measured. Antihypertensive effects and smooths index of diastolic blood pressure in Valsartan and Hydrochorothatizide group were better than Valsartan or Hydrochorothatizide group. Uric acid of hydrochorothatizide increased, but there were no changes in other groups. The three groups had no adverse effects on serum lipids, blood glucose, electrolyte, function of live and kidney. The combination of Valsartan with Hydrochorothatizide was safety, stability and effective against hypertension, which were better than single drug. Valsartan had beneficial effects in decrease uric acid. Am J Hypertens (2004) 17, 111A–112A; doi: 10.1016/j.amjhyper.2004.03.289" @default.
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- W2032083415 date "2004-05-01" @default.
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- W2032083415 title "Efficacy and safety of combination of valsartan with hydrochorothatizide in the management of patients with essential hypertension" @default.
- W2032083415 doi "https://doi.org/10.1016/j.amjhyper.2004.03.289" @default.
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