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- W2032083828 abstract "An improved version of the J-based NMR configurational analysis of flexible organic molecules, that relies on extensive use of HSQC-TOCSY spectra, was applied to the stereochemical study of sphinxolide, a potent anti-tumor marine macrolide acting on cell microfilaments that has lately proven to circumvent multi-drug-resistance (MDR) in cancer cells. NMR data allowed stereochemical assignment of all molecular segments except the C18−C19 unit, whose configuration had to be addressed by a chemical/degradative approach." @default.
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- W2032083828 date "2001-01-01" @default.
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- W2032083828 title "Stereochemical Studies on Sphinxolide: Advances in theJ-Based NMR Determination of the Relative Configuration of Flexible Systems" @default.
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- W2032083828 doi "https://doi.org/10.1002/1099-0690(200101)2001:1<39::aid-ejoc39>3.0.co;2-9" @default.
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