FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032097154> ?p ?o ?g. }

• W2032097154 endingPage "6" @default.
• W2032097154 startingPage "1" @default.
• W2032097154 abstract "Intronless genes (IGs) constitute approximately 3% of the human genome. Human IGs are essentially different in evolution and functionality from the IGs of unicellular eukaryotes, which represent the majority in their genomes. Functional analysis of IGs has revealed a massive over-representation of signal transduction genes and genes encoding regulatory proteins important for growth, proliferation, and development. IGs also often display tissue-specific expression, usually in the nervous system and testis. These characteristics translate into IG-associated diseases, mainly neuropathies, developmental disorders, and cancer. IGs represent recent additions to the genome, created mostly by retroposition of processed mRNAs with retained functionality. Processing, nuclear export, and translation of these mRNAs should be hampered dramatically by the lack of splice factors, which normally tightly cover mature transcripts and govern their fate. However, natural IGs manage to maintain satisfactory expression levels. Different mechanisms by which IGs solve the problem of mRNA processing and nuclear export are discussed here, along with their possible impact on reporter studies." @default.
• W2032097154 created "2016-06-24" @default.
• W2032097154 creator A5038778361 @default.
• W2032097154 date "2012-07-01" @default.
• W2032097154 modified "2023-10-14" @default.
• W2032097154 title "Human intronless genes: Functional groups, associated diseases, evolution, and mRNA processing in absence of splicing" @default.
• W2032097154 cites W192453652 @default.
• W2032097154 cites W1946993828 @default.
• W2032097154 cites W1964779657 @default.
• W2032097154 cites W1971074826 @default.
• W2032097154 cites W1974434328 @default.
• W2032097154 cites W1977820220 @default.
• W2032097154 cites W1981036063 @default.
• W2032097154 cites W1987008065 @default.
• W2032097154 cites W1993287040 @default.
• W2032097154 cites W1999081551 @default.
• W2032097154 cites W2003462362 @default.
• W2032097154 cites W2006301581 @default.
• W2032097154 cites W2006931677 @default.
• W2032097154 cites W2009183437 @default.
• W2032097154 cites W2013160020 @default.
• W2032097154 cites W2013277487 @default.
• W2032097154 cites W2014179433 @default.
• W2032097154 cites W2019222179 @default.
• W2032097154 cites W2027159300 @default.
• W2032097154 cites W2028190503 @default.
• W2032097154 cites W2037094815 @default.
• W2032097154 cites W2038809664 @default.
• W2032097154 cites W2046370446 @default.
• W2032097154 cites W2046498307 @default.
• W2032097154 cites W2074244754 @default.
• W2032097154 cites W2078810064 @default.
• W2032097154 cites W2079671119 @default.
• W2032097154 cites W2096507957 @default.
• W2032097154 cites W2101756535 @default.
• W2032097154 cites W2102680897 @default.
• W2032097154 cites W2104098418 @default.
• W2032097154 cites W2104627343 @default.
• W2032097154 cites W2106102246 @default.
• W2032097154 cites W2107866906 @default.
• W2032097154 cites W2114891593 @default.
• W2032097154 cites W2115744888 @default.
• W2032097154 cites W2121210720 @default.
• W2032097154 cites W2123067735 @default.
• W2032097154 cites W2133205331 @default.
• W2032097154 cites W2139905086 @default.
• W2032097154 cites W2141029670 @default.
• W2032097154 cites W2142639875 @default.
• W2032097154 cites W2147507101 @default.
• W2032097154 cites W2154925328 @default.
• W2032097154 cites W2157253966 @default.
• W2032097154 cites W2159391740 @default.
• W2032097154 cites W2165256190 @default.
• W2032097154 cites W2166428615 @default.
• W2032097154 cites W2169315049 @default.
• W2032097154 cites W2171305498 @default.
• W2032097154 cites W2240027552 @default.
• W2032097154 cites W4244845911 @default.
• W2032097154 doi "https://doi.org/10.1016/j.bbrc.2012.06.092" @default.
• W2032097154 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22732409" @default.
• W2032097154 hasPublicationYear "2012" @default.
• W2032097154 type Work @default.
• W2032097154 sameAs 2032097154 @default.
• W2032097154 citedByCount "78" @default.
• W2032097154 countsByYear W20320971542012 @default.
• W2032097154 countsByYear W20320971542013 @default.
• W2032097154 countsByYear W20320971542014 @default.
• W2032097154 countsByYear W20320971542015 @default.
• W2032097154 countsByYear W20320971542016 @default.
• W2032097154 countsByYear W20320971542017 @default.
• W2032097154 countsByYear W20320971542018 @default.
• W2032097154 countsByYear W20320971542019 @default.
• W2032097154 countsByYear W20320971542020 @default.
• W2032097154 countsByYear W20320971542021 @default.
• W2032097154 countsByYear W20320971542022 @default.
• W2032097154 countsByYear W20320971542023 @default.
• W2032097154 crossrefType "journal-article" @default.
• W2032097154 hasAuthorship W2032097154A5038778361 @default.
• W2032097154 hasConcept C104317684 @default.
• W2032097154 hasConcept C105580179 @default.
• W2032097154 hasConcept C141231307 @default.
• W2032097154 hasConcept C149364088 @default.
• W2032097154 hasConcept C150194340 @default.
• W2032097154 hasConcept C194583182 @default.
• W2032097154 hasConcept C197077220 @default.
• W2032097154 hasConcept C54355233 @default.
• W2032097154 hasConcept C54458228 @default.
• W2032097154 hasConcept C67705224 @default.
• W2032097154 hasConcept C70721500 @default.
• W2032097154 hasConcept C86803240 @default.
• W2032097154 hasConcept C94671646 @default.
• W2032097154 hasConceptScore W2032097154C104317684 @default.
• W2032097154 hasConceptScore W2032097154C105580179 @default.
• W2032097154 hasConceptScore W2032097154C141231307 @default.
• W2032097154 hasConceptScore W2032097154C149364088 @default.
• W2032097154 hasConceptScore W2032097154C150194340 @default.
• W2032097154 hasConceptScore W2032097154C194583182 @default.
• W2032097154 hasConceptScore W2032097154C197077220 @default.

• next