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• W2032127966 abstract "This study consists of the bioassay-guided fractionation of the dichloromethane extract from Eudistoma vannamei and the pharmacological characterization of the active fractions. The dried hydromethanolic extract dissolved in aqueous methanol was partitioned with dichloromethane and chromatographed on a silica gel flash column. The anti-proliferative effect was monitored by the MTT assay. Four of the latest fractions, numbered 14 to 17, which held many chemical similarities amongst each other, were found to be the most active. The selected fractions were tested for viability, proliferation and death induction on cultures of HL-60 promyeloblastic leukemia cells. The results suggested that the observed cytotoxicity is related to apoptosis induction." @default.
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• W2032127966 date "2008-11-01" @default.
• W2032127966 modified "2023-10-11" @default.
• W2032127966 title "Cytotoxic activity of a dichloromethane extract and fractions obtained from Eudistoma vannamei (Tunicata: Ascidiacea)" @default.
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• W2032127966 doi "https://doi.org/10.1016/j.cbpa.2007.02.018" @default.
• W2032127966 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17400012" @default.
• W2032127966 hasPublicationYear "2008" @default.
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