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- W2032129292 abstract "A 53-year-old African American man with HIV disease, poor compliance with medical treatment, CD4 count of 1 cell/mL (normal: 500-1500 cell/mL), and viral load of >100,000 RNA copies/mL (undetectable) presented with intermittent bright red blood per rectum for 3 years, with increased frequency 2 weeks before admission. Physical examination was unremarkable except for tachycardia. Initial laboratory results showed anemia with Hb, 6.5 g/dL (12-18 g/dL). Stool studies were not obtained. Upper endoscopy revealed whitish esophageal plaques consistent with Candida esophagitis infection. Colonoscopy demonstrated multiple ulcers with raised margins throughout the colon (Figure 1, Figure 2). Biopsy specimens of the ulcers showed colitis, ulceration, and Toxoplasma gondii organisms within the ulcer bed (Figure 3, Figure 4). Magnetic resonance imaging, with gadolinium contrast, of the brain showed numerous ring-enhancing lesions. The patient was treated with pyrimethamine, sulfadiazine, and folate, resulting in diarrhea resolution. Figure 2Endoscopic view of the colon, showing a mucosal ulcer. View Large Image Figure Viewer Figure 3Photomicrograph of colonic biopsy specimens, showing a tachyzoite (H&E, orig. mag. ×400). View Large Image Figure Viewer Figure 4Photomicrograph of colonic biopsy specimens, showing tachyzoites (immunohistochemistry staining, orig. mag. ×400). View Large Image Figure Viewer" @default.
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- W2032129292 date "2006-02-01" @default.
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- W2032129292 title "Toxoplasma colitis in a patient with acquired immune deficiency syndrome" @default.
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- W2032129292 doi "https://doi.org/10.1016/j.gie.2005.09.001" @default.
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