FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032187763> ?p ?o ?g. }

• W2032187763 endingPage "1852" @default.
• W2032187763 startingPage "1842" @default.
• W2032187763 abstract "Internal ribosome entry site (IRES) elements govern protein synthesis of mRNAs that bypass cap-dependent translation inhibition under stress conditions. Picornavirus IRES are cis-acting elements, organized in modular domains that recruit the ribosome to internal mRNA sites. The aim of this study was to retrieve short RNA sequences with the capacity to adopt RNA folding patterns conserved with IRES structural subdomains, likely corresponding to RNA modules. We have applied a new program, RNAiFold, an inverse folding algorithm that determines all sequences whose minimum free energy structure is identical to that of the structural domains of interest. Sequences differing by more than 1 nt were clustered. Then, BLASTing one randomly chosen sequence from each cluster of the RNAiFold output, we retrieved viral and cellular sequences among output hits. As a proof of principle, we present the data corresponding to a coding region of Drosophila melanogaster TAF6, a transcription factor-associated protein that contains a structural motif within its coding region potentially folding into an IRES-like subdomain. This RNA region shows a biased codon usage, as predicted from structural constraints at the RNA level, it harbors conserved IRES structural motifs in loops, and interestingly, it has the capacity to confer internal initiation of translation in tissue culture cells." @default.
• W2032187763 created "2016-06-24" @default.
• W2032187763 creator A5038146612 @default.
• W2032187763 creator A5038186958 @default.
• W2032187763 creator A5059708538 @default.
• W2032187763 creator A5082352339 @default.
• W2032187763 date "2013-12-01" @default.
• W2032187763 modified "2023-10-04" @default.
• W2032187763 title "Using RNA inverse folding to identify IRES-like structural subdomains" @default.
• W2032187763 cites W1489126106 @default.
• W2032187763 cites W1507397164 @default.
• W2032187763 cites W164172871 @default.
• W2032187763 cites W1831381424 @default.
• W2032187763 cites W1920564293 @default.
• W2032187763 cites W1967369040 @default.
• W2032187763 cites W1970949525 @default.
• W2032187763 cites W1977964738 @default.
• W2032187763 cites W1978109916 @default.
• W2032187763 cites W1978313170 @default.
• W2032187763 cites W1985957104 @default.
• W2032187763 cites W1986778616 @default.
• W2032187763 cites W1987059370 @default.
• W2032187763 cites W1991192984 @default.
• W2032187763 cites W2012818607 @default.
• W2032187763 cites W2014790936 @default.
• W2032187763 cites W2016107719 @default.
• W2032187763 cites W2020077467 @default.
• W2032187763 cites W2029451306 @default.
• W2032187763 cites W2030449053 @default.
• W2032187763 cites W2033713984 @default.
• W2032187763 cites W2036166416 @default.
• W2032187763 cites W2037500442 @default.
• W2032187763 cites W2042129026 @default.
• W2032187763 cites W2045715626 @default.
• W2032187763 cites W2045843097 @default.
• W2032187763 cites W2046498307 @default.
• W2032187763 cites W2052918843 @default.
• W2032187763 cites W2070083583 @default.
• W2032187763 cites W2073785087 @default.
• W2032187763 cites W2073982917 @default.
• W2032187763 cites W2087072039 @default.
• W2032187763 cites W2092108158 @default.
• W2032187763 cites W2093213907 @default.
• W2032187763 cites W2096585562 @default.
• W2032187763 cites W2097000233 @default.
• W2032187763 cites W2100049196 @default.
• W2032187763 cites W2102304447 @default.
• W2032187763 cites W2111342151 @default.
• W2032187763 cites W2119582819 @default.
• W2032187763 cites W2121918723 @default.
• W2032187763 cites W2122944508 @default.
• W2032187763 cites W2123140971 @default.
• W2032187763 cites W2123551500 @default.
• W2032187763 cites W2125615424 @default.
• W2032187763 cites W2135373808 @default.
• W2032187763 cites W2136095036 @default.
• W2032187763 cites W2143407915 @default.
• W2032187763 cites W2144671815 @default.
• W2032187763 cites W2147362276 @default.
• W2032187763 cites W2151923909 @default.
• W2032187763 cites W2152974876 @default.
• W2032187763 cites W2154241726 @default.
• W2032187763 cites W2157868062 @default.
• W2032187763 cites W2166409098 @default.
• W2032187763 cites W2166706771 @default.
• W2032187763 cites W2171940869 @default.
• W2032187763 cites W4250052351 @default.
• W2032187763 doi "https://doi.org/10.4161/rna.26994" @default.
• W2032187763 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3917987" @default.
• W2032187763 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24253111" @default.
• W2032187763 hasPublicationYear "2013" @default.
• W2032187763 type Work @default.
• W2032187763 sameAs 2032187763 @default.
• W2032187763 citedByCount "20" @default.
• W2032187763 countsByYear W20321877632014 @default.
• W2032187763 countsByYear W20321877632015 @default.
• W2032187763 countsByYear W20321877632016 @default.
• W2032187763 countsByYear W20321877632017 @default.
• W2032187763 countsByYear W20321877632018 @default.
• W2032187763 countsByYear W20321877632019 @default.
• W2032187763 countsByYear W20321877632020 @default.
• W2032187763 countsByYear W20321877632023 @default.
• W2032187763 crossrefType "journal-article" @default.
• W2032187763 hasAuthorship W2032187763A5038146612 @default.
• W2032187763 hasAuthorship W2032187763A5038186958 @default.
• W2032187763 hasAuthorship W2032187763A5059708538 @default.
• W2032187763 hasAuthorship W2032187763A5082352339 @default.
• W2032187763 hasBestOaLocation W20321877631 @default.
• W2032187763 hasConcept C104317684 @default.
• W2032187763 hasConcept C105580179 @default.
• W2032187763 hasConcept C126142528 @default.
• W2032187763 hasConcept C132677234 @default.
• W2032187763 hasConcept C149364088 @default.
• W2032187763 hasConcept C4718897 @default.
• W2032187763 hasConcept C54355233 @default.
• W2032187763 hasConcept C55493867 @default.
• W2032187763 hasConcept C67705224 @default.
• W2032187763 hasConcept C70721500 @default.

• next