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- W2032197839 abstract "We compare the relative efficacy of high dose rate (HDR) and low dose rate (LDR) irradiation in gynecological implants, using formulations based on the linear-quadratic (alpha-beta) model. We consider both acute reaction and late effect as endpoints in evaluating equivalence for HDR and LDR treatments, at Point A (as defined in the text) and at other locations. We define a therapeutic factor gamma as an index for relative efficacy, with gamma > 1 indicating a gain in substituting HDR for LDR. It is found that gamma < 1 for most clinical situations, although a modest decrease (of about 15%) in dose to critical organs for HDR would raise gamma above unity." @default.
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- W2032197839 date "1992-10-01" @default.
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- W2032197839 title "High dose rate gynecological applications — radiobiological considerations based on the α-β model" @default.
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- W2032197839 doi "https://doi.org/10.1016/0167-8140(92)90016-n" @default.
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