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• W2032238400 endingPage "532" @default.
• W2032238400 startingPage "515" @default.
• W2032238400 abstract "Alpha-2 agonists, such as xylazine, clonidine, romifidine, detomidine, medetomidine, and dexmedetomidine, are potent analgesic drugs that also induce physiologic and behavioral changes, such as hypertension, bradycardia, atrioventricular block, excessive sedation and ataxia, all of which can potentially limit their systemic use as analgesics in some clinical cases. The use of medetomidine and dexmetomidine has been introduced for equine anesthesia/analgesia, and although not approved in this species, their increased specificity for alpha-2 receptors may offer some potential advantages over the traditional alpha-2 agonists. Similarly, other routes of administration and benefits of alpha-2 agonists are recognized in the human and laboratory animal literature, which may prove useful in the equine patient if validated in the near future. This review presents this relevant information." @default.
• W2032238400 created "2016-06-24" @default.
• W2032238400 creator A5023964705 @default.
• W2032238400 date "2010-12-01" @default.
• W2032238400 modified "2023-10-18" @default.
• W2032238400 title "Alpha-2 Agonists as Pain Therapy in Horses" @default.
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• W2032238400 doi "https://doi.org/10.1016/j.cveq.2010.07.003" @default.
• W2032238400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21056297" @default.
• W2032238400 hasPublicationYear "2010" @default.

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