FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032244641> ?p ?o ?g. }

• W2032244641 endingPage "93" @default.
• W2032244641 startingPage "88" @default.
• W2032244641 abstract "Purpose Whole breast irradiation (WBI) is the standard of care for patients with early-stage breast cancer who opt for breast conservation. After a randomized trial demonstrated equivalent cosmesis and disease control with accelerated WBI (AWBI), our institution began to offer AWBI to appropriate patients. The aim of this study was to examine our unique experience with AWBI using prone positioning and simplified intensity-modulated radiotherapy (IMRT) planning with a sequential boost to the tumor bed. Methods and Materials We identified 356 patients who had been treated with prone WBI using IMRT in our department between January 2004 and December 2006. Of these, 128 (36%) patients had received AWBI (representing 131 treated breasts), consisting of 16 daily fractions of 265 cGy to a total dose of 4,240 cGy followed by a conventionally fractionated boost. Results Patients who opted for AWBI were similar demographically to the patients undergoing conventional WBI. In the AWBI cohort, 83% of the patients had Stage T1 disease and 22% had nodal involvement (N1). The tumors were estrogen receptor-positive, progesterone receptor-positive and Her-2/Neu-amplified in 82%, 69%, and 11%, respectively. The median duration of AWBI plus a boost was 29 days, and no patient required a toxicity-related treatment break. No Grade 3 or greater acute toxicity developed. At a median follow-up of 18 months, one ipsilateral breast recurrence developed that was salvaged with mastectomy and immediate reconstruction. Conclusion AWBI to the prone breast using simplified IMRT with a sequential boost offers women requiring breast-only adjuvant radiotherapy an abbreviated treatment with early tumor control and cosmesis comparable to that with standard fractionation. Whole breast irradiation (WBI) is the standard of care for patients with early-stage breast cancer who opt for breast conservation. After a randomized trial demonstrated equivalent cosmesis and disease control with accelerated WBI (AWBI), our institution began to offer AWBI to appropriate patients. The aim of this study was to examine our unique experience with AWBI using prone positioning and simplified intensity-modulated radiotherapy (IMRT) planning with a sequential boost to the tumor bed. We identified 356 patients who had been treated with prone WBI using IMRT in our department between January 2004 and December 2006. Of these, 128 (36%) patients had received AWBI (representing 131 treated breasts), consisting of 16 daily fractions of 265 cGy to a total dose of 4,240 cGy followed by a conventionally fractionated boost. Patients who opted for AWBI were similar demographically to the patients undergoing conventional WBI. In the AWBI cohort, 83% of the patients had Stage T1 disease and 22% had nodal involvement (N1). The tumors were estrogen receptor-positive, progesterone receptor-positive and Her-2/Neu-amplified in 82%, 69%, and 11%, respectively. The median duration of AWBI plus a boost was 29 days, and no patient required a toxicity-related treatment break. No Grade 3 or greater acute toxicity developed. At a median follow-up of 18 months, one ipsilateral breast recurrence developed that was salvaged with mastectomy and immediate reconstruction. AWBI to the prone breast using simplified IMRT with a sequential boost offers women requiring breast-only adjuvant radiotherapy an abbreviated treatment with early tumor control and cosmesis comparable to that with standard fractionation." @default.
• W2032244641 created "2016-06-24" @default.
• W2032244641 creator A5012372987 @default.
• W2032244641 creator A5022293657 @default.
• W2032244641 creator A5032257865 @default.
• W2032244641 creator A5049280981 @default.
• W2032244641 date "2009-01-01" @default.
• W2032244641 modified "2023-10-16" @default.
• W2032244641 title "Accelerated Whole Breast Irradiation With Intensity-Modulated Radiotherapy to the Prone Breast" @default.
• W2032244641 cites W1831225282 @default.
• W2032244641 cites W1966642934 @default.
• W2032244641 cites W1967961719 @default.
• W2032244641 cites W1968724321 @default.
• W2032244641 cites W1980606545 @default.
• W2032244641 cites W1988173928 @default.
• W2032244641 cites W1990531876 @default.
• W2032244641 cites W1990963883 @default.
• W2032244641 cites W1998405893 @default.
• W2032244641 cites W1999465640 @default.
• W2032244641 cites W2002054274 @default.
• W2032244641 cites W2007256049 @default.
• W2032244641 cites W2017880906 @default.
• W2032244641 cites W2018835161 @default.
• W2032244641 cites W2022677800 @default.
• W2032244641 cites W2040868890 @default.
• W2032244641 cites W2040953448 @default.
• W2032244641 cites W2057655643 @default.
• W2032244641 cites W2066215197 @default.
• W2032244641 cites W2078467934 @default.
• W2032244641 cites W2101429637 @default.
• W2032244641 cites W2119491010 @default.
• W2032244641 cites W2120560566 @default.
• W2032244641 cites W2143899676 @default.
• W2032244641 cites W2145380278 @default.
• W2032244641 cites W2150874458 @default.
• W2032244641 cites W2156724578 @default.
• W2032244641 cites W2158615473 @default.
• W2032244641 cites W2169031890 @default.
• W2032244641 cites W2170163382 @default.
• W2032244641 cites W4235149737 @default.
• W2032244641 doi "https://doi.org/10.1016/j.ijrobp.2008.04.036" @default.
• W2032244641 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18676095" @default.
• W2032244641 hasPublicationYear "2009" @default.
• W2032244641 type Work @default.
• W2032244641 sameAs 2032244641 @default.
• W2032244641 citedByCount "24" @default.
• W2032244641 countsByYear W20322446412012 @default.
• W2032244641 countsByYear W20322446412013 @default.
• W2032244641 countsByYear W20322446412014 @default.
• W2032244641 countsByYear W20322446412015 @default.
• W2032244641 countsByYear W20322446412016 @default.
• W2032244641 countsByYear W20322446412017 @default.
• W2032244641 countsByYear W20322446412018 @default.
• W2032244641 countsByYear W20322446412020 @default.
• W2032244641 countsByYear W20322446412021 @default.
• W2032244641 crossrefType "journal-article" @default.
• W2032244641 hasAuthorship W2032244641A5012372987 @default.
• W2032244641 hasAuthorship W2032244641A5022293657 @default.
• W2032244641 hasAuthorship W2032244641A5032257865 @default.
• W2032244641 hasAuthorship W2032244641A5049280981 @default.
• W2032244641 hasConcept C121608353 @default.
• W2032244641 hasConcept C126322002 @default.
• W2032244641 hasConcept C126838900 @default.
• W2032244641 hasConcept C141071460 @default.
• W2032244641 hasConcept C143998085 @default.
• W2032244641 hasConcept C146357865 @default.
• W2032244641 hasConcept C151730666 @default.
• W2032244641 hasConcept C2777757722 @default.
• W2032244641 hasConcept C2777863537 @default.
• W2032244641 hasConcept C2780943399 @default.
• W2032244641 hasConcept C2781467025 @default.
• W2032244641 hasConcept C2989005 @default.
• W2032244641 hasConcept C509974204 @default.
• W2032244641 hasConcept C530470458 @default.
• W2032244641 hasConcept C71924100 @default.
• W2032244641 hasConcept C72563966 @default.
• W2032244641 hasConcept C86803240 @default.
• W2032244641 hasConceptScore W2032244641C121608353 @default.
• W2032244641 hasConceptScore W2032244641C126322002 @default.
• W2032244641 hasConceptScore W2032244641C126838900 @default.
• W2032244641 hasConceptScore W2032244641C141071460 @default.
• W2032244641 hasConceptScore W2032244641C143998085 @default.
• W2032244641 hasConceptScore W2032244641C146357865 @default.
• W2032244641 hasConceptScore W2032244641C151730666 @default.
• W2032244641 hasConceptScore W2032244641C2777757722 @default.
• W2032244641 hasConceptScore W2032244641C2777863537 @default.
• W2032244641 hasConceptScore W2032244641C2780943399 @default.
• W2032244641 hasConceptScore W2032244641C2781467025 @default.
• W2032244641 hasConceptScore W2032244641C2989005 @default.
• W2032244641 hasConceptScore W2032244641C509974204 @default.
• W2032244641 hasConceptScore W2032244641C530470458 @default.
• W2032244641 hasConceptScore W2032244641C71924100 @default.
• W2032244641 hasConceptScore W2032244641C72563966 @default.
• W2032244641 hasConceptScore W2032244641C86803240 @default.
• W2032244641 hasIssue "1" @default.
• W2032244641 hasLocation W20322446411 @default.
• W2032244641 hasLocation W20322446412 @default.
• W2032244641 hasOpenAccess W2032244641 @default.

• next