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- W2032256724 abstract "In an electron microscopic study, actinomycin D produced typical nucleolar segregation in hepatic parenchymal cells and intestinal crypt cells of male rats in which prior inhibition of protein synthesis had been induced with cycloheximide. A dose of actinomycin D which produces typical segregation in hepatic parenchymal cells produces only partial segregation of the nucleoli of intestinal crypt cells. Typical segregation can be produced in the latter by prolonging the actinomycin treatment and increasing the dose. The segregation phenomenon demonstrates that the large particle component of crypt cell nucleoli represents a population distinct from the small particles of the nucleolonema of these cells." @default.
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- W2032256724 title "Induction of nucleolar segregation by actinomycin D following inhibition of protein synthesis with cycloheximide" @default.
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- W2032256724 doi "https://doi.org/10.1016/0014-4827(70)90338-1" @default.
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