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- W2032269748 abstract "Nielsen, O. H. and Schiøtz, P. O. (Paediatric Department TG, Rigshospitalet, Copenhagen, Denmark). Cystic fibrosis in Denmark in the period 1945-1981. Acta Paediatr Scand 1982; suppl 301: 107-119. — The present study gives a re-evaluation of the course of the prognosis for cystic fibrosis (CF) in Denmark in the period January 1, 1945 — September 15, 1981. A total of 490 patients fulfilled the criteria of entry. Despite a rather constant annual incidence, the number of surviving CF patients is highly increasing: thus 31 patients were alive as on December 31, 1960, 119 as on December 31, 1970, and 223 as on December 31, 1980. The survival was further evaluated using the decrement method, where the patients are entered by time of birth or time of diagnosis, and the Warwick & Monson method, where the patients are entered by time of diagnosis. It applies to both methods that the underlying patient populations did not include patients with meconium ileus and patients with a retrospective or autopsy diagnosis. The probability of reaching the age of 10 years was 52% for CF patients treated exclusively in departments other than the CF centre as compared to 84% for the CF centre patients. We conclude that the centralized treatment should be preserved for a so relatively uncommon disease as CF, both because our survival curves demonstrated the prognosis to be by far the better in the patients treated at the national CF centre and because centralized treatment alone can offer appropriate research conditions." @default.
- W2032269748 created "2016-06-24" @default.
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- W2032269748 date "1982-10-01" @default.
- W2032269748 modified "2023-09-23" @default.
- W2032269748 title "CYSTIC FIBROSIS IN DENMARK IN THE PERIOD 1945-1981 EVALUATION OF CENTRALIZED TREATMENT" @default.
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- W2032269748 doi "https://doi.org/10.1111/j.1651-2227.1982.tb09645.x" @default.
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