FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032313503> ?p ?o ?g. }

• W2032313503 endingPage "10" @default.
• W2032313503 startingPage "1" @default.
• W2032313503 abstract "Shi-Liu-Wei-Liu-Qi-Yin (SLWLQY) was traditionally used to treat cancers. However, scientific evidence of the anticancer effects still remains undefined. In this study, we aimed to clarify the possible mechanisms of SLWLQY in treating cancer. We evaluated the effects of SLWLQY on apoptosis-related experiments inducing in TSGH-8301 cells by (i) 3-(4,5-dimethylthiazol-zyl)-2,5-diphenylterazolium bromide (MTT) for cytotoxicity; (ii) cell-cycle analysis and (iii) western blot analysis of the G2/M-phase and apoptosis regulatory proteins. Human bladder carcinoma TSGH-8301 cells were transplanted into BALB/c nude mice as a tumor model for evaluating the antitumor effect of SLWLQY. Treatment of SLWLQY resulted in the G2/M phase arrest and apoptotic death in a dose-dependent manner, accompanied by a decrease in cyclin-dependent kinases (cdc2) and cyclins (cyclin B1). SLWLQY stimulated increases in the protein expression of Fas and FasL, and induced the cleavage of caspase-3, caspase-9 and caspase-8. The ratio of Bax/Bcl 2 was increased by SLWLQY treatment. SLWLQY markedly reduced tumor size in TSGH-8301 cells-xenografted tumor tissues. In the tissue specimen, SLWLQY up-regulated the expression of Fas, FasL and Bax proteins, and down-regulated Bcl 2 as well as in in vitro assay. Our results showed that SLWLQY reduced tumor growth, caused cell-cycle arrest and apoptosis in TSGH-8301 cells via the Fas and mitochondrial pathway." @default.
• W2032313503 created "2016-06-24" @default.
• W2032313503 creator A5030790757 @default.
• W2032313503 creator A5035906051 @default.
• W2032313503 creator A5052693926 @default.
• W2032313503 creator A5074105906 @default.
• W2032313503 creator A5075181003 @default.
• W2032313503 date "2011-01-01" @default.
• W2032313503 modified "2023-10-18" @default.
• W2032313503 title "Aqueous Extract of Shi-Liu-Wei-Liu-Qi-Yin Induces G2/M Phase Arrest and Apoptosis in Human Bladder Carcinoma Cells via Fas and Mitochondrial Pathway" @default.
• W2032313503 cites W1968144640 @default.
• W2032313503 cites W1977219317 @default.
• W2032313503 cites W1994349020 @default.
• W2032313503 cites W2001866564 @default.
• W2032313503 cites W2013595164 @default.
• W2032313503 cites W2041603571 @default.
• W2032313503 cites W2045000096 @default.
• W2032313503 cites W2060213890 @default.
• W2032313503 cites W2078003307 @default.
• W2032313503 cites W2082259697 @default.
• W2032313503 cites W2088388419 @default.
• W2032313503 cites W2093467508 @default.
• W2032313503 cites W2106123852 @default.
• W2032313503 cites W2115023106 @default.
• W2032313503 cites W2124385784 @default.
• W2032313503 cites W2125988618 @default.
• W2032313503 cites W2130866079 @default.
• W2032313503 cites W2140707911 @default.
• W2032313503 cites W2144701362 @default.
• W2032313503 cites W2151501496 @default.
• W2032313503 cites W2155853588 @default.
• W2032313503 cites W2163962048 @default.
• W2032313503 cites W2164236001 @default.
• W2032313503 cites W4211039187 @default.
• W2032313503 cites W85124676 @default.
• W2032313503 doi "https://doi.org/10.1093/ecam/nep016" @default.
• W2032313503 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3135273" @default.
• W2032313503 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19383839" @default.
• W2032313503 hasPublicationYear "2011" @default.
• W2032313503 type Work @default.
• W2032313503 sameAs 2032313503 @default.
• W2032313503 citedByCount "4" @default.
• W2032313503 countsByYear W20323135032013 @default.
• W2032313503 countsByYear W20323135032016 @default.
• W2032313503 crossrefType "journal-article" @default.
• W2032313503 hasAuthorship W2032313503A5030790757 @default.
• W2032313503 hasAuthorship W2032313503A5035906051 @default.
• W2032313503 hasAuthorship W2032313503A5052693926 @default.
• W2032313503 hasAuthorship W2032313503A5074105906 @default.
• W2032313503 hasAuthorship W2032313503A5075181003 @default.
• W2032313503 hasBestOaLocation W20323135031 @default.
• W2032313503 hasConcept C105696609 @default.
• W2032313503 hasConcept C120089663 @default.
• W2032313503 hasConcept C120504264 @default.
• W2032313503 hasConcept C12519072 @default.
• W2032313503 hasConcept C153911025 @default.
• W2032313503 hasConcept C185592680 @default.
• W2032313503 hasConcept C190283241 @default.
• W2032313503 hasConcept C2775975398 @default.
• W2032313503 hasConcept C2778437423 @default.
• W2032313503 hasConcept C29537977 @default.
• W2032313503 hasConcept C31573885 @default.
• W2032313503 hasConcept C48297814 @default.
• W2032313503 hasConcept C502942594 @default.
• W2032313503 hasConcept C55493867 @default.
• W2032313503 hasConcept C66008609 @default.
• W2032313503 hasConcept C86803240 @default.
• W2032313503 hasConceptScore W2032313503C105696609 @default.
• W2032313503 hasConceptScore W2032313503C120089663 @default.
• W2032313503 hasConceptScore W2032313503C120504264 @default.
• W2032313503 hasConceptScore W2032313503C12519072 @default.
• W2032313503 hasConceptScore W2032313503C153911025 @default.
• W2032313503 hasConceptScore W2032313503C185592680 @default.
• W2032313503 hasConceptScore W2032313503C190283241 @default.
• W2032313503 hasConceptScore W2032313503C2775975398 @default.
• W2032313503 hasConceptScore W2032313503C2778437423 @default.
• W2032313503 hasConceptScore W2032313503C29537977 @default.
• W2032313503 hasConceptScore W2032313503C31573885 @default.
• W2032313503 hasConceptScore W2032313503C48297814 @default.
• W2032313503 hasConceptScore W2032313503C502942594 @default.
• W2032313503 hasConceptScore W2032313503C55493867 @default.
• W2032313503 hasConceptScore W2032313503C66008609 @default.
• W2032313503 hasConceptScore W2032313503C86803240 @default.
• W2032313503 hasLocation W20323135031 @default.
• W2032313503 hasLocation W20323135032 @default.
• W2032313503 hasLocation W20323135033 @default.
• W2032313503 hasLocation W20323135034 @default.
• W2032313503 hasLocation W20323135035 @default.
• W2032313503 hasOpenAccess W2032313503 @default.
• W2032313503 hasPrimaryLocation W20323135031 @default.
• W2032313503 hasRelatedWork W2029191005 @default.
• W2032313503 hasRelatedWork W2032313503 @default.
• W2032313503 hasRelatedWork W2074039448 @default.
• W2032313503 hasRelatedWork W2178706579 @default.
• W2032313503 hasRelatedWork W2358077472 @default.
• W2032313503 hasRelatedWork W2366272921 @default.
• W2032313503 hasRelatedWork W2370759520 @default.
• W2032313503 hasRelatedWork W2403889419 @default.

• next