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• W2032416947 abstract "Several 7-alkoxy-4-anilino-3-quinolinecarbonitriles were synthesized and evaluated for Src kinase inhibitory activity. Optimal inhibition of both Src enzymatic and cellular activity was seen with analogues having a 2,4-dichloro-5-methoxyaniline group at C-4. Compound 18, which has a 1-methylpiperidinemethoxy group at C-7, showed in vivo activity in a xenograft model." @default.
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• W2032416947 date "2003-11-01" @default.
• W2032416947 modified "2023-09-26" @default.
• W2032416947 title "Investigation of the effect of varying the 4-anilino and 7-alkoxy groups of 3-quinolinecarbonitriles on the inhibition of Src kinase activity" @default.
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• W2032416947 doi "https://doi.org/10.1016/j.bmcl.2003.07.001" @default.
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