FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032443863> ?p ?o ?g. }

• W2032443863 endingPage "656" @default.
• W2032443863 startingPage "649" @default.
• W2032443863 abstract "Oligodendrocytes are myelinating cells of the CNS that originate as progenitor cells (OP) in discrete areas of the developing brain. During brain development, OP migrate significant distances prior to proliferating and myelinating the axons of the putative white matter tracts. Growth factors play a major regulatory role in the behavior of OP. Specifically, platelet-derived growth factor A (PDGF-A) and fibroblast growth factor 2 (FGF2) are two of the most well characterized regulators of OP development. Both growth factors interact with tyrosine kinase receptors, activating various intracellular signaling pathways. The current study advances our earlier research by comparing the effects of both PDGF-A and FGF2 on OP migration. Our results show that activation of ERK is required for OP migration. These findings correlate well with our previous demonstration of the ERK pathway mediating PDGF-A induced OP migration. We also demonstrate the significance of threshold levels of growth factors and temporal regulation for OP migration. In addition, ERK activation alone is not sufficient to induce OP migration. The current research supports the involvement of the non-ERK mediated signaling pathway in OP migration." @default.
• W2032443863 created "2016-06-24" @default.
• W2032443863 creator A5006210481 @default.
• W2032443863 creator A5025515531 @default.
• W2032443863 creator A5026792355 @default.
• W2032443863 creator A5030470992 @default.
• W2032443863 creator A5043563044 @default.
• W2032443863 creator A5058756187 @default.
• W2032443863 date "2011-08-01" @default.
• W2032443863 modified "2023-10-04" @default.
• W2032443863 title "Differential effects of growth factors on oligodendrocyte progenitor migration" @default.
• W2032443863 cites W1608092431 @default.
• W2032443863 cites W1790384858 @default.
• W2032443863 cites W1896545635 @default.
• W2032443863 cites W1948282121 @default.
• W2032443863 cites W1953992154 @default.
• W2032443863 cites W1963891523 @default.
• W2032443863 cites W1966879473 @default.
• W2032443863 cites W1967529127 @default.
• W2032443863 cites W1968091333 @default.
• W2032443863 cites W1969642134 @default.
• W2032443863 cites W1969647408 @default.
• W2032443863 cites W1970510801 @default.
• W2032443863 cites W1971671659 @default.
• W2032443863 cites W1975417481 @default.
• W2032443863 cites W1977103562 @default.
• W2032443863 cites W1977218716 @default.
• W2032443863 cites W1980286364 @default.
• W2032443863 cites W1983389236 @default.
• W2032443863 cites W1985309285 @default.
• W2032443863 cites W1989439339 @default.
• W2032443863 cites W1992245559 @default.
• W2032443863 cites W1998225973 @default.
• W2032443863 cites W2001585146 @default.
• W2032443863 cites W2001642942 @default.
• W2032443863 cites W2007209145 @default.
• W2032443863 cites W2011557383 @default.
• W2032443863 cites W2012228544 @default.
• W2032443863 cites W2013681684 @default.
• W2032443863 cites W2016831735 @default.
• W2032443863 cites W2025488020 @default.
• W2032443863 cites W2030534632 @default.
• W2032443863 cites W2032833236 @default.
• W2032443863 cites W2032980424 @default.
• W2032443863 cites W2034601315 @default.
• W2032443863 cites W2039397457 @default.
• W2032443863 cites W2041096852 @default.
• W2032443863 cites W2041678520 @default.
• W2032443863 cites W2042478816 @default.
• W2032443863 cites W2049548683 @default.
• W2032443863 cites W2050601632 @default.
• W2032443863 cites W2056664397 @default.
• W2032443863 cites W2056983875 @default.
• W2032443863 cites W2058119565 @default.
• W2032443863 cites W2064168648 @default.
• W2032443863 cites W2065968106 @default.
• W2032443863 cites W2067005574 @default.
• W2032443863 cites W2067340278 @default.
• W2032443863 cites W2070640008 @default.
• W2032443863 cites W2073807475 @default.
• W2032443863 cites W2074747649 @default.
• W2032443863 cites W2076682664 @default.
• W2032443863 cites W2077642701 @default.
• W2032443863 cites W2081560586 @default.
• W2032443863 cites W2086262311 @default.
• W2032443863 cites W2097557938 @default.
• W2032443863 cites W2097761970 @default.
• W2032443863 cites W2100837269 @default.
• W2032443863 cites W2107625098 @default.
• W2032443863 cites W2110121929 @default.
• W2032443863 cites W2124134886 @default.
• W2032443863 cites W2128351119 @default.
• W2032443863 cites W2130044807 @default.
• W2032443863 cites W2138178479 @default.
• W2032443863 cites W2139485237 @default.
• W2032443863 cites W2142745956 @default.
• W2032443863 cites W2147893091 @default.
• W2032443863 cites W2154198214 @default.
• W2032443863 cites W2157065140 @default.
• W2032443863 cites W2161123040 @default.
• W2032443863 cites W2166039202 @default.
• W2032443863 cites W2344579286 @default.
• W2032443863 cites W4211075026 @default.
• W2032443863 cites W4293247451 @default.
• W2032443863 doi "https://doi.org/10.1016/j.ejcb.2011.03.006" @default.
• W2032443863 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21616555" @default.
• W2032443863 hasPublicationYear "2011" @default.
• W2032443863 type Work @default.
• W2032443863 sameAs 2032443863 @default.
• W2032443863 citedByCount "19" @default.
• W2032443863 countsByYear W20324438632012 @default.
• W2032443863 countsByYear W20324438632013 @default.
• W2032443863 countsByYear W20324438632014 @default.
• W2032443863 countsByYear W20324438632015 @default.
• W2032443863 countsByYear W20324438632016 @default.
• W2032443863 countsByYear W20324438632017 @default.
• W2032443863 countsByYear W20324438632018 @default.
• W2032443863 countsByYear W20324438632019 @default.

• next