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• W2032488049 endingPage "11236" @default.
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• W2032488049 abstract "The syntheses and structures of three new coordinatively unsaturated, monomeric, square-pyramidal thiolate-ligated Fe(III) complexes are described, [Fe(III)((tame-N(3))S(2)(Me2))](+) (1), [Fe(III)(Et-N(2)S(2)(Me2))(py)](1-) (3), and [Fe(III)((tame-N(2)S)S(2)(Me2))](2-) (15). The anionic bis-carboxamide, tris-thiolate N(2)S(3) coordination sphere of 15 is potentially similar to that of the yet-to-be characterized unmodified form of NHase. Comparison of the magnetic and reactivity properties of these reveals how anionic charge build up (from cationic 1 to anionic 3 and dianionic 15) and spin-state influence apical ligand affinity. For all of the ligand-field combinations examined, an intermediate S = 3/2 spin state was shown to be favored by a strong N(2)S(2) basal plane ligand field, and this was found to reduce the affinity for apical ligands, even when they are built in. This is in contrast to the post-translationally modified NHase active site, which is low spin and displays a higher affinity for apical ligands. Cationic 1 and its reduced Fe(II) precursor are shown to bind NO and CO, respectively, to afford [Fe(III)((tame-N(3))S(2)(Me))(NO)](+) (18, nu(NuO) = 1865 cm(-1)), an analogue of NO-inactivated NHase, and [Fe(II)((tame-N(3))S(2)(Me))(CO)] (16; nu(CO) stretch (1895 cm(-1)). Anions (N(3)(-), CN(-)) are shown to be unreactive toward 1, 3, and 15 and neutral ligands unreactive toward 3 and 15, even when present in 100-fold excess and at low temperatures. The curtailed reactivity of 15, an analogue of the unmodified form of NHase, and its apical-oxygenated S = 3/2 derivative [Fe(III)((tame-N(2)SO(2))S(2)(Me2))](2-) (20) suggests that regioselective post-translational oxygenation of the basal plane NHase cysteinate sulfurs plays an important role in promoting substrate binding. This is supported by previously reported theoretical (DFT) calculations." @default.
• W2032488049 created "2016-06-24" @default.
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• W2032488049 date "2008-11-07" @default.
• W2032488049 modified "2023-09-23" @default.
• W2032488049 title "Properties of Square-Pyramidal Alkyl−Thiolate Fe^III Complexes, Including an Analogue of the Unmodified Form of Nitrile Hydratase" @default.
• W2032488049 cites W1967700647 @default.
• W2032488049 cites W1968639674 @default.
• W2032488049 cites W1970019531 @default.
• W2032488049 cites W1970974930 @default.
• W2032488049 cites W1971325685 @default.
• W2032488049 cites W1975968619 @default.
• W2032488049 cites W1978443199 @default.
• W2032488049 cites W1978882556 @default.
• W2032488049 cites W1979002359 @default.
• W2032488049 cites W1983777334 @default.
• W2032488049 cites W1985018007 @default.
• W2032488049 cites W1985704056 @default.
• W2032488049 cites W1991941342 @default.
• W2032488049 cites W1995985124 @default.
• W2032488049 cites W1998852717 @default.
• W2032488049 cites W1998953779 @default.
• W2032488049 cites W2004721157 @default.
• W2032488049 cites W2006886510 @default.
• W2032488049 cites W2009159004 @default.
• W2032488049 cites W2013962744 @default.
• W2032488049 cites W2016656463 @default.
• W2032488049 cites W2019082288 @default.
• W2032488049 cites W2020647583 @default.
• W2032488049 cites W2022991766 @default.
• W2032488049 cites W2024541714 @default.
• W2032488049 cites W2024694966 @default.
• W2032488049 cites W2029875006 @default.
• W2032488049 cites W2029976844 @default.
• W2032488049 cites W2030182333 @default.
• W2032488049 cites W2032421968 @default.
• W2032488049 cites W2040708326 @default.
• W2032488049 cites W2040956342 @default.
• W2032488049 cites W2049668900 @default.
• W2032488049 cites W2050097723 @default.
• W2032488049 cites W2050603831 @default.
• W2032488049 cites W2052824028 @default.
• W2032488049 cites W2053445234 @default.
• W2032488049 cites W2055517776 @default.
• W2032488049 cites W2056175395 @default.
• W2032488049 cites W2058201918 @default.
• W2032488049 cites W2060738076 @default.
• W2032488049 cites W2061395334 @default.
• W2032488049 cites W2063184595 @default.
• W2032488049 cites W2063917761 @default.
• W2032488049 cites W2065094516 @default.
• W2032488049 cites W2066625233 @default.
• W2032488049 cites W2070412343 @default.
• W2032488049 cites W2079983041 @default.
• W2032488049 cites W2081473613 @default.
• W2032488049 cites W2084229335 @default.
• W2032488049 cites W2085354396 @default.
• W2032488049 cites W2087890020 @default.
• W2032488049 cites W2090832229 @default.
• W2032488049 cites W2091501139 @default.
• W2032488049 cites W2093467529 @default.
• W2032488049 cites W2093500730 @default.
• W2032488049 cites W2094204173 @default.
• W2032488049 cites W2095188041 @default.
• W2032488049 cites W2100317545 @default.
• W2032488049 cites W2102249406 @default.
• W2032488049 cites W2103477311 @default.
• W2032488049 cites W2105249240 @default.
• W2032488049 cites W2107174565 @default.
• W2032488049 cites W2125930374 @default.
• W2032488049 cites W2133098487 @default.
• W2032488049 cites W2136901578 @default.
• W2032488049 cites W2141459263 @default.
• W2032488049 cites W2142464470 @default.
• W2032488049 cites W2153003355 @default.
• W2032488049 cites W2157473097 @default.
• W2032488049 cites W2158514585 @default.
• W2032488049 cites W2950135852 @default.
• W2032488049 cites W2951053628 @default.
• W2032488049 cites W2951903792 @default.
• W2032488049 cites W3005496877 @default.
• W2032488049 doi "https://doi.org/10.1021/ic801704n" @default.
• W2032488049 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2659597" @default.
• W2032488049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18989922" @default.
• W2032488049 hasPublicationYear "2008" @default.
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