Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032488413> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2032488413 abstract "The objective of the present work is to develop stability indicating high-performance liquid chromatographic method for the simultaneous determination of aminexil and minoxidil in pharmaceutical dosage form. The chromatographic separation was achieved with BDS Hypersil C18 column (250 mm×4.6 mm×5 μ) as stationary phase and phosphate buffer and acetonitrile (78:22) as mobile phase. The method was employed by using a flow rate of 1.1 mL/min kept at 30°C. The detection wavelength was kept at 238 nm by using photo-diode array detector. The retention times of the aminexil and minoxidil were found to be 2.3 min and 3.9 min, respectively. The method developed was validated in accordance with ICH guidelines with respect to the stability indicating capacity of the method including system suitability, accuracy, precision, linearity, range, limit of detection, limit of quantification and robustness. The linearity responses of aminexil and minoxidil were found to be in the concentration ranges of 18.75-112.5 μg/mL and 25-150 μg/mL, respectively. The LOD and LOQ values for aminexil were found to be 0.31 and 0.92 μg/mL and minoxidil were found to be 0.03 and 0.10 μg/mL respectively. The percentage recoveries for both the drugs were found in the range of 98-101%. This method is accurate, precise and sensitive; hence, it can be employed for routine quality control of aminexil and minoxidil in pharmaceutical industries and drug testing laboratories." @default.
- W2032488413 created "2016-06-24" @default.
- W2032488413 creator A5009319968 @default.
- W2032488413 creator A5065153376 @default.
- W2032488413 date "2015-03-01" @default.
- W2032488413 modified "2023-10-16" @default.
- W2032488413 title "Stability indicating RP-HPLC method development and validation for the simultaneous determination of aminexil and minoxidil in pharmaceutical dosage form" @default.
- W2032488413 cites W1518576429 @default.
- W2032488413 cites W170728667 @default.
- W2032488413 cites W1971984162 @default.
- W2032488413 cites W1978071277 @default.
- W2032488413 cites W1990798711 @default.
- W2032488413 cites W2044206509 @default.
- W2032488413 cites W2062473650 @default.
- W2032488413 cites W2068215665 @default.
- W2032488413 cites W2068677258 @default.
- W2032488413 cites W2078822186 @default.
- W2032488413 cites W2079030766 @default.
- W2032488413 cites W2082003630 @default.
- W2032488413 cites W2082948487 @default.
- W2032488413 cites W2090580627 @default.
- W2032488413 cites W2102925803 @default.
- W2032488413 cites W2112652287 @default.
- W2032488413 cites W2152493786 @default.
- W2032488413 cites W2587374672 @default.
- W2032488413 cites W2592168936 @default.
- W2032488413 cites W2942719587 @default.
- W2032488413 cites W632623301 @default.
- W2032488413 doi "https://doi.org/10.1016/j.pharma.2014.10.005" @default.
- W2032488413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25542653" @default.
- W2032488413 hasPublicationYear "2015" @default.
- W2032488413 type Work @default.
- W2032488413 sameAs 2032488413 @default.
- W2032488413 citedByCount "1" @default.
- W2032488413 countsByYear W20324884132020 @default.
- W2032488413 crossrefType "journal-article" @default.
- W2032488413 hasAuthorship W2032488413A5009319968 @default.
- W2032488413 hasAuthorship W2032488413A5065153376 @default.
- W2032488413 hasConcept C106186310 @default.
- W2032488413 hasConcept C113196181 @default.
- W2032488413 hasConcept C119128265 @default.
- W2032488413 hasConcept C121332964 @default.
- W2032488413 hasConcept C16005928 @default.
- W2032488413 hasConcept C179998833 @default.
- W2032488413 hasConcept C185592680 @default.
- W2032488413 hasConcept C2777463227 @default.
- W2032488413 hasConcept C2779711729 @default.
- W2032488413 hasConcept C43617362 @default.
- W2032488413 hasConcept C62520636 @default.
- W2032488413 hasConcept C71924100 @default.
- W2032488413 hasConcept C77170095 @default.
- W2032488413 hasConcept C77281830 @default.
- W2032488413 hasConcept C96616956 @default.
- W2032488413 hasConceptScore W2032488413C106186310 @default.
- W2032488413 hasConceptScore W2032488413C113196181 @default.
- W2032488413 hasConceptScore W2032488413C119128265 @default.
- W2032488413 hasConceptScore W2032488413C121332964 @default.
- W2032488413 hasConceptScore W2032488413C16005928 @default.
- W2032488413 hasConceptScore W2032488413C179998833 @default.
- W2032488413 hasConceptScore W2032488413C185592680 @default.
- W2032488413 hasConceptScore W2032488413C2777463227 @default.
- W2032488413 hasConceptScore W2032488413C2779711729 @default.
- W2032488413 hasConceptScore W2032488413C43617362 @default.
- W2032488413 hasConceptScore W2032488413C62520636 @default.
- W2032488413 hasConceptScore W2032488413C71924100 @default.
- W2032488413 hasConceptScore W2032488413C77170095 @default.
- W2032488413 hasConceptScore W2032488413C77281830 @default.
- W2032488413 hasConceptScore W2032488413C96616956 @default.
- W2032488413 hasLocation W20324884131 @default.
- W2032488413 hasLocation W20324884132 @default.
- W2032488413 hasOpenAccess W2032488413 @default.
- W2032488413 hasPrimaryLocation W20324884131 @default.
- W2032488413 hasRelatedWork W1552592887 @default.
- W2032488413 hasRelatedWork W1977798251 @default.
- W2032488413 hasRelatedWork W1995375582 @default.
- W2032488413 hasRelatedWork W2046604074 @default.
- W2032488413 hasRelatedWork W2061854528 @default.
- W2032488413 hasRelatedWork W2092407583 @default.
- W2032488413 hasRelatedWork W2581635834 @default.
- W2032488413 hasRelatedWork W3108081678 @default.
- W2032488413 hasRelatedWork W2185382761 @default.
- W2032488413 hasRelatedWork W2186695557 @default.
- W2032488413 isParatext "false" @default.
- W2032488413 isRetracted "false" @default.
- W2032488413 magId "2032488413" @default.
- W2032488413 workType "article" @default.