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- W2032505144 abstract "The linguomandibular reflex (LMR) is a polysynaptic reflex involving interneurons within the brain stem. Electrical stimulation of areas in the basal ganglia have been shown to influence this reflex. The effect of known antiparkinson drugs on the linguomandibular reflex in cats investigated. 1-Dopa and apomorphine poduced dose-related inhibition of the LMR whereas amantadine and benztropine were ineffective. Apomorphine-induced inhibition of the LMR was antagonized surmountably by haloperidol, a relatively specific dopamine antagonist but not by phenoxybenzamine, an α-adrenergic blocking agent. 1-Dopa-induced inhibition of the LMR was not antagonized by either haloperidol or phenoxybenzamine. Known metabolites of 1-dopa, dopamine and norepinephrine were tested for their effects on the LMR and none was more potent than 1-dopa. These results suggest that 1-dopa might inhibit the LMR via a direct effect of its own." @default.
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- W2032505144 date "1973-02-01" @default.
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- W2032505144 title "The effect of antiparkinson drugs on the linguomandibular reflex in cats" @default.
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- W2032505144 doi "https://doi.org/10.1016/0014-2999(73)90223-9" @default.
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