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• W2032583364 abstract "Seventy-four patients treated for squamous cell carcinoma (SCC) of the nasopharynx were evaluated for the5-year survival rate. The influence of stage, age, histological differentiation, total tumour dose and irradiation treatment technique (continuous vs. split-course) upon the survival was evaluated in 64 patients (palliations and histologically unclassified SCC were excluded). The 5-year survival rate in the whole group was 28/74 (38%), and in the group without palliations and unclassified SCC 26/64 (41%). The 5-year survival of patients with T1 carcinoma was better (8/9=89%) than of patients with T2 (4/14=29%), T3 (7/17=41%) and T4 (7/24=29%) carcinoma. In the group of 55 patients with T2, T3 and T4 carcinoma, those up to 50 years old had better survival (11/21=52%) than patients older than 50 years (7/34=21%) (p<0.01), patients treated with the tumour dose >65 Gy had better survival (16/38=42%) than those treated with 50–65 Gy (2/17=12%) (p<0.05), and patients older than 50 years, with poorly differentiated carcinoma had better survival (7/20=35%) than those of the same age, with well-differentiated carcinoma (0/14=0%) (p<0.005). The split-course irradiation technique did not improve the 5-year survival rate, although on average the total tumour dose in this type of treatment was for 7.9 Gy higher than in the continuous irradiation. Seventy-four patients treated for squamous cell carcinoma (SCC) of the nasopharynx were evaluated for the5-year survival rate. The influence of stage, age, histological differentiation, total tumour dose and irradiation treatment technique (continuous vs. split-course) upon the survival was evaluated in 64 patients (palliations and histologically unclassified SCC were excluded). The 5-year survival rate in the whole group was 28/74 (38%), and in the group without palliations and unclassified SCC 26/64 (41%). The 5-year survival of patients with T1 carcinoma was better (8/9=89%) than of patients with T2 (4/14=29%), T3 (7/17=41%) and T4 (7/24=29%) carcinoma. In the group of 55 patients with T2, T3 and T4 carcinoma, those up to 50 years old had better survival (11/21=52%) than patients older than 50 years (7/34=21%) (p<0.01), patients treated with the tumour dose >65 Gy had better survival (16/38=42%) than those treated with 50–65 Gy (2/17=12%) (p<0.05), and patients older than 50 years, with poorly differentiated carcinoma had better survival (7/20=35%) than those of the same age, with well-differentiated carcinoma (0/14=0%) (p<0.005). The split-course irradiation technique did not improve the 5-year survival rate, although on average the total tumour dose in this type of treatment was for 7.9 Gy higher than in the continuous irradiation." @default.
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• W2032583364 title "Carcinoma of the nasopharynx: Results of radiation treatment and some prognostic factors" @default.
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• W2032583364 doi "https://doi.org/10.1016/s0167-8140(87)80019-1" @default.
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