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- W2032712850 abstract "Deoxyadenosine, deoxyguanosine, deoxycytidine; thymidine and a dinucleotide, 2'-deoxycytidylyl-(3'-5')-2'-deoxythymidine (dCdT), were reacted with 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX). Nucleoside HPLC analysis revealed that the major products are the degradation products of MX and no stable MX-adducts were found. The same result was obtained with sodium borohydride reduction. The fluorescence spectra of deoxyguanosine-MX showed no fluorescence at neutral or alkaline pH, indicating no binding products to the N2-groups of deoxyguanosine." @default.
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- W2032712850 date "1991-04-01" @default.
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- W2032712850 title "Assay for nucleoside and nucleotide binding of a potent mutagen, 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone" @default.
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- W2032712850 doi "https://doi.org/10.1016/0378-4274(91)90103-d" @default.
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