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• W2032720565 abstract "Infection of the human lymphocyte CEM cell line with the HIV-1 (human immunodeficiency virus-1, LAV-1 strain) results in cell death. A fluoroquinolone antibiotic, ofloxacin, protected the infected cells from HIV-1-mediated cytolysis. Other fluoroquinolones, e.g. ciprofloxacin, norfloxacin, and enoxacin, also protected the infected cells from HIV-1-mediated cytolysis. The d-isomer of ofloxacin (DR-3354) was about 50-fold less effective than the l-isomer (DR-3355). Almost none of the rescued cells had detectable HIV-antigens and they could be maintained for long periods in vitro without drugs." @default.
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• W2032720565 date "1990-01-01" @default.
• W2032720565 modified "2023-10-03" @default.
• W2032720565 title "Fluoroquinolones protect the human lymphocyte CEM cell line from HIV-1-mediated cytotoxicity." @default.
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• W2032720565 doi "https://doi.org/10.1247/csf.15.295" @default.
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