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- W2032737334 abstract "TYK2 is a member of the janus protein kinase family and plays an important role in the signal transduction of various cytokines including interferon alpha/beta. Cloning and characterization of the porcine TYK2 gene revealed a conserved organization with respect to other mammalian TYK2 orthologs. The porcine gene consists of 25 exons spanning approximately 26 kb and encoding a 5.3-kb mRNA. It is located in a GC-rich and gene-rich chromosome region and contains several CpG islands. The predicted 132-kDa TYK2 protein consists of 1,184 amino acids and shows 85% identity to the human TYK2 protein. The porcine TYK2 gene was localized by FISH and RH-mapping on SSC 2q1.3-->q2.1, which is in good agreement with established human-mouse-pig comparative maps." @default.
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- W2032737334 date "2004-08-18" @default.
- W2032737334 modified "2023-10-18" @default.
- W2032737334 title "Molecular characterization of the porcine TYK2 gene on SSC 2q1.3→q2.1" @default.
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- W2032737334 doi "https://doi.org/10.1159/000079578" @default.
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