Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032776082> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2032776082 endingPage "1076" @default.
- W2032776082 startingPage "1069" @default.
- W2032776082 abstract "A kinetic study of atosiban was conducted following repeated intravenous administration in Wistar rats. Sample analysis was performed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) following full validation of an in-house method. Eptifibatide, a cyclic peptide, was used as an internal standard (IS). The analyte and internal standard were extracted using solid phase extraction (SPE) method. Chromatographic separation was carried out using an ACE C18 5 microm 50 mm x 4.6 mm column with gradient elution. Mass spectrometric detection was performed using TSQ Quantum ultra AM. The lower limit of quantification was 0.01 microg/ml when 100 microl rat plasma was used. Plasma concentrations of atosiban were measured at 0 (pre-dose), 2, 15, 30, 45, 60, 120 min at the dosage levels of 0.125 mg/kg (low dose), 0.250 mg/kg (mid dose), and 0.500 mg/kg (high dose), respectively. Atosiban plasma concentration measured at Day 1 showed mean peak atosiban concentration (C(max)) 0.40, 0.57, 1.95 microg/ml for low, mid and high dose treated animals and mean peak concentration on Day 28 was 0.41, 0.88, 1.31microg/ml on Day 28 for low, mid and high dose treated animals." @default.
- W2032776082 created "2016-06-24" @default.
- W2032776082 creator A5005519616 @default.
- W2032776082 creator A5006769740 @default.
- W2032776082 creator A5015963245 @default.
- W2032776082 creator A5027764959 @default.
- W2032776082 creator A5029572770 @default.
- W2032776082 creator A5043223536 @default.
- W2032776082 creator A5049918333 @default.
- W2032776082 creator A5083079481 @default.
- W2032776082 creator A5084898940 @default.
- W2032776082 date "2010-05-01" @default.
- W2032776082 modified "2023-09-27" @default.
- W2032776082 title "Quantitative determination of oxytocin receptor antagonist atosiban in rat plasma by liquid chromatography–tandem mass spectrometry" @default.
- W2032776082 cites W1967803345 @default.
- W2032776082 cites W1983312160 @default.
- W2032776082 cites W1995352085 @default.
- W2032776082 cites W1995778137 @default.
- W2032776082 cites W2010337985 @default.
- W2032776082 cites W2019706074 @default.
- W2032776082 cites W2046112092 @default.
- W2032776082 cites W2047323052 @default.
- W2032776082 cites W2051058627 @default.
- W2032776082 cites W2095662990 @default.
- W2032776082 cites W2100786900 @default.
- W2032776082 cites W2105420615 @default.
- W2032776082 cites W2114766280 @default.
- W2032776082 cites W2136174167 @default.
- W2032776082 cites W2150139527 @default.
- W2032776082 cites W2158594359 @default.
- W2032776082 doi "https://doi.org/10.1016/j.jchromb.2010.03.011" @default.
- W2032776082 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20356809" @default.
- W2032776082 hasPublicationYear "2010" @default.
- W2032776082 type Work @default.
- W2032776082 sameAs 2032776082 @default.
- W2032776082 citedByCount "6" @default.
- W2032776082 countsByYear W20327760822012 @default.
- W2032776082 countsByYear W20327760822013 @default.
- W2032776082 countsByYear W20327760822014 @default.
- W2032776082 countsByYear W20327760822020 @default.
- W2032776082 countsByYear W20327760822022 @default.
- W2032776082 crossrefType "journal-article" @default.
- W2032776082 hasAuthorship W2032776082A5005519616 @default.
- W2032776082 hasAuthorship W2032776082A5006769740 @default.
- W2032776082 hasAuthorship W2032776082A5015963245 @default.
- W2032776082 hasAuthorship W2032776082A5027764959 @default.
- W2032776082 hasAuthorship W2032776082A5029572770 @default.
- W2032776082 hasAuthorship W2032776082A5043223536 @default.
- W2032776082 hasAuthorship W2032776082A5049918333 @default.
- W2032776082 hasAuthorship W2032776082A5083079481 @default.
- W2032776082 hasAuthorship W2032776082A5084898940 @default.
- W2032776082 hasConcept C119128265 @default.
- W2032776082 hasConcept C134018914 @default.
- W2032776082 hasConcept C162356407 @default.
- W2032776082 hasConcept C179998833 @default.
- W2032776082 hasConcept C185592680 @default.
- W2032776082 hasConcept C2776176026 @default.
- W2032776082 hasConcept C31827203 @default.
- W2032776082 hasConcept C43617362 @default.
- W2032776082 hasConcept C4725764 @default.
- W2032776082 hasConcept C64489805 @default.
- W2032776082 hasConcept C71924100 @default.
- W2032776082 hasConcept C81426234 @default.
- W2032776082 hasConcept C95986675 @default.
- W2032776082 hasConceptScore W2032776082C119128265 @default.
- W2032776082 hasConceptScore W2032776082C134018914 @default.
- W2032776082 hasConceptScore W2032776082C162356407 @default.
- W2032776082 hasConceptScore W2032776082C179998833 @default.
- W2032776082 hasConceptScore W2032776082C185592680 @default.
- W2032776082 hasConceptScore W2032776082C2776176026 @default.
- W2032776082 hasConceptScore W2032776082C31827203 @default.
- W2032776082 hasConceptScore W2032776082C43617362 @default.
- W2032776082 hasConceptScore W2032776082C4725764 @default.
- W2032776082 hasConceptScore W2032776082C64489805 @default.
- W2032776082 hasConceptScore W2032776082C71924100 @default.
- W2032776082 hasConceptScore W2032776082C81426234 @default.
- W2032776082 hasConceptScore W2032776082C95986675 @default.
- W2032776082 hasIssue "15-16" @default.
- W2032776082 hasLocation W20327760821 @default.
- W2032776082 hasLocation W20327760822 @default.
- W2032776082 hasOpenAccess W2032776082 @default.
- W2032776082 hasPrimaryLocation W20327760821 @default.
- W2032776082 hasRelatedWork W1603333022 @default.
- W2032776082 hasRelatedWork W1973119017 @default.
- W2032776082 hasRelatedWork W1997103078 @default.
- W2032776082 hasRelatedWork W2044206509 @default.
- W2032776082 hasRelatedWork W2074088656 @default.
- W2032776082 hasRelatedWork W2078713560 @default.
- W2032776082 hasRelatedWork W2086902282 @default.
- W2032776082 hasRelatedWork W2153596481 @default.
- W2032776082 hasRelatedWork W2359574775 @default.
- W2032776082 hasRelatedWork W2384044203 @default.
- W2032776082 hasVolume "878" @default.
- W2032776082 isParatext "false" @default.
- W2032776082 isRetracted "false" @default.
- W2032776082 magId "2032776082" @default.
- W2032776082 workType "article" @default.