FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2032778425> ?p ?o ?g. }

• W2032778425 endingPage "279" @default.
• W2032778425 startingPage "273" @default.
• W2032778425 abstract "Polyclonal anti-thymocyte globulins (ATGs) are used to induce immunosuppression and to treat acute rejection after transplantation. ATGs induce apoptosis and in peripheral T-lymphocytes having the potential to inhibit leukocyte adhesion. We analysed the influence of three different ATGs upon the microvasculature and the different cell-subpopulations after ischemia/reperfusion (IRI). Extremities of cynomolgus monkeys were surgically isolated and flushed with Ringer's lactate at 4 °C. After 60 min of ischemia the limbs were reperfused with matching human blood. ATGs were added to the blood 30 min prior to the reperfusion. Four groups were generated: Tecelac-ATG group, Fresenius(S)-ATG group, Thymoglobulin-ATG group and a control group. Blood analyses were performed in blood samples taken after the beginning of the reperfusion. Biopsies from muscular tissue were obtained after the experiments. The number of circulating leukocytes was lower in the ATG-groups than in control. Morpho-cytological analyses showed depletion of peripheral lymphocytes. Histological examination showed less tissue damage, reduced presence of fibrin and adherent thrombocytes in the ATG-treated groups. Leukocyte infiltration, both in muscle and vascular structures, was significantly diminished in the ATG-groups in comparison to control. Our results show that ATGs have a favourable impact on early mechanisms of IRI. ATGs showed a reduction of the number of adherent leukocytes and muscle infiltrates suggesting that preoperative therapy with ATGs may have an advantageous effect on primary non-function and on chronic rejection as well as a positive influence upon IRI." @default.
• W2032778425 created "2016-06-24" @default.
• W2032778425 creator A5006547618 @default.
• W2032778425 creator A5016510047 @default.
• W2032778425 creator A5058435779 @default.
• W2032778425 creator A5070545892 @default.
• W2032778425 date "2006-04-01" @default.
• W2032778425 modified "2023-10-16" @default.
• W2032778425 title "Influence of polyclonal anti-thymocyte globulins upon ischemia–reperfusion injury in a non-human primate model" @default.
• W2032778425 cites W1571274258 @default.
• W2032778425 cites W1682167319 @default.
• W2032778425 cites W1967872436 @default.
• W2032778425 cites W1971917654 @default.
• W2032778425 cites W1999369912 @default.
• W2032778425 cites W2018100390 @default.
• W2032778425 cites W2026843743 @default.
• W2032778425 cites W2047383048 @default.
• W2032778425 cites W2049963602 @default.
• W2032778425 cites W2054236565 @default.
• W2032778425 cites W2060508116 @default.
• W2032778425 cites W2066131635 @default.
• W2032778425 cites W2066697125 @default.
• W2032778425 cites W2079138844 @default.
• W2032778425 cites W2085299861 @default.
• W2032778425 cites W2090232993 @default.
• W2032778425 cites W2092332908 @default.
• W2032778425 cites W2110555251 @default.
• W2032778425 cites W2121127245 @default.
• W2032778425 cites W2144728936 @default.
• W2032778425 cites W2146135235 @default.
• W2032778425 cites W2167207140 @default.
• W2032778425 cites W2262851522 @default.
• W2032778425 cites W2324306112 @default.
• W2032778425 cites W2413040204 @default.
• W2032778425 cites W4243996621 @default.
• W2032778425 doi "https://doi.org/10.1016/j.trim.2006.02.003" @default.
• W2032778425 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16635749" @default.
• W2032778425 hasPublicationYear "2006" @default.
• W2032778425 type Work @default.
• W2032778425 sameAs 2032778425 @default.
• W2032778425 citedByCount "41" @default.
• W2032778425 countsByYear W20327784252012 @default.
• W2032778425 countsByYear W20327784252014 @default.
• W2032778425 countsByYear W20327784252015 @default.
• W2032778425 countsByYear W20327784252016 @default.
• W2032778425 countsByYear W20327784252018 @default.
• W2032778425 countsByYear W20327784252019 @default.
• W2032778425 countsByYear W20327784252020 @default.
• W2032778425 countsByYear W20327784252021 @default.
• W2032778425 countsByYear W20327784252022 @default.
• W2032778425 countsByYear W20327784252023 @default.
• W2032778425 crossrefType "journal-article" @default.
• W2032778425 hasAuthorship W2032778425A5006547618 @default.
• W2032778425 hasAuthorship W2032778425A5016510047 @default.
• W2032778425 hasAuthorship W2032778425A5058435779 @default.
• W2032778425 hasAuthorship W2032778425A5070545892 @default.
• W2032778425 hasConcept C126322002 @default.
• W2032778425 hasConcept C142724271 @default.
• W2032778425 hasConcept C16685009 @default.
• W2032778425 hasConcept C203014093 @default.
• W2032778425 hasConcept C2776090121 @default.
• W2032778425 hasConcept C2778954852 @default.
• W2032778425 hasConcept C2780114680 @default.
• W2032778425 hasConcept C2780882860 @default.
• W2032778425 hasConcept C541997718 @default.
• W2032778425 hasConcept C71924100 @default.
• W2032778425 hasConcept C81358767 @default.
• W2032778425 hasConcept C8891405 @default.
• W2032778425 hasConceptScore W2032778425C126322002 @default.
• W2032778425 hasConceptScore W2032778425C142724271 @default.
• W2032778425 hasConceptScore W2032778425C16685009 @default.
• W2032778425 hasConceptScore W2032778425C203014093 @default.
• W2032778425 hasConceptScore W2032778425C2776090121 @default.
• W2032778425 hasConceptScore W2032778425C2778954852 @default.
• W2032778425 hasConceptScore W2032778425C2780114680 @default.
• W2032778425 hasConceptScore W2032778425C2780882860 @default.
• W2032778425 hasConceptScore W2032778425C541997718 @default.
• W2032778425 hasConceptScore W2032778425C71924100 @default.
• W2032778425 hasConceptScore W2032778425C81358767 @default.
• W2032778425 hasConceptScore W2032778425C8891405 @default.
• W2032778425 hasIssue "4" @default.
• W2032778425 hasLocation W20327784251 @default.
• W2032778425 hasLocation W20327784252 @default.
• W2032778425 hasOpenAccess W2032778425 @default.
• W2032778425 hasPrimaryLocation W20327784251 @default.
• W2032778425 hasRelatedWork W2033078839 @default.
• W2032778425 hasRelatedWork W2039266031 @default.
• W2032778425 hasRelatedWork W2063380779 @default.
• W2032778425 hasRelatedWork W2090226487 @default.
• W2032778425 hasRelatedWork W2133676382 @default.
• W2032778425 hasRelatedWork W2318369866 @default.
• W2032778425 hasRelatedWork W2332949591 @default.
• W2032778425 hasRelatedWork W3063455412 @default.
• W2032778425 hasRelatedWork W3210051868 @default.
• W2032778425 hasRelatedWork W4241609410 @default.
• W2032778425 hasVolume "15" @default.
• W2032778425 isParatext "false" @default.
• W2032778425 isRetracted "false" @default.

• next