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- W2032882022 abstract "Rajput et al. have published a paper entitled “Essential tremor is not dependent upon Purkinje cell loss” [ [1] Rajput A.H. Robinson C.A. Rajput M.L. Robinson S.L. Rajput A. Essential tremor is not dependent upon cerebellar Purkinje cell loss. Parkinsonism Relat Disord. 2012 Feb 2; ([Epub ahead of print]) PubMed Google Scholar ]. As in their earlier report [ [2] Rajput A.H. Robinson C.A. Rajput M.L. Rajput A. Cerebellar Purkinje cell loss is not pathognomonic of essential tremor. Parkinsonism Relat Disord. 2011; 17: 16-21 Abstract Full Text Full Text PDF PubMed Scopus (33) Google Scholar ], to which we have also responded [ [3] Louis E.D. Faust P.L. Vonsattel J.P. Purkinje cell loss is a characteristic of essential tremor. Parkinsonism Relat Disord. 2011; 17: 406-409 Abstract Full Text Full Text PDF PubMed Scopus (36) Google Scholar ], there are methodological and conceptual issues that we would like to raise. The goal of these communications is to try to enrich the dialogue in this field. Importantly, there are underlying areas of agreement. Essential tremor is not dependent upon cerebellar Purkinje cell lossParkinsonism & Related DisordersVol. 18Issue 5PreviewThe pathophysiology of essential tremor (ET) is unknown but recent studies report that the majority of ET cases has cerebellar Purkinje cell (PC) degeneration and its sequelae. Full-Text PDF Purkinje cell loss is neither pathological basis nor characteristic of essential tremorParkinsonism & Related DisordersVol. 19Issue 4PreviewWe read with interest the letter by Louis et al. [1]. Full-Text PDF" @default.
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- W2032882022 date "2012-09-01" @default.
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- W2032882022 title "Purkinje cell loss is a characteristic of essential tremor: Towards a more mature understanding of pathogenesis" @default.
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