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- W2032892974 abstract "Three patients with persistent cutaneous leishmania infection of 8-, 14- and 30-year duration, respectively, and with demonstrable delayed hypersensitivity to leishmania antigens were treated with leishmania-specific transfer factor prepared from healthy donors with a previous history of cutaneous leishmania infection. The cutaneous lesions healed completely in all three cases. The total dose of transfer factor required to achieve healing was much higher than the dose used by other investigators. The results justify a further clinical trial to determine the therapeutic effectiveness of transfer factor in cutaneous leishmaniasis. Further, because the infective agent is neither ubiquitous nor homogeneous, cutaneous leishmania infection in man offers a unique opportunity for a double blind study aimed at evaluating the therapeutic usefulness of transfer factor in human intracellular infections and further analytic studies to determine both the in vivo and in vitro specificity of transfer factor." @default.
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- W2032892974 date "1979-02-01" @default.
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- W2032892974 title "Preliminary results of transfer factor therapy of persistant cutaneous leishmania infection" @default.
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- W2032892974 doi "https://doi.org/10.1016/0090-1229(79)90007-2" @default.
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