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• W2032931168 abstract "With high diagnostic performance, 320-slice computed tomography angiography (CTA) is a viable alternative to invasive coronary angiography (ICA) for ruling out coronary artery disease [ [1] Li S. Ni Q. Wu H. et al. Diagnostic accuracy of 320-slice computed tomography angiography for detection of coronary artery stenosis: meta-analysis. Int J Cardiol. Apr 5 2013; 168: 2699-2705 Abstract Full Text Full Text PDF PubMed Scopus (43) Google Scholar ]. However, the potential risk of contrast-induced nephropathy (CIN) in the process of CT scan is connected with increased morbidity, prolonged hospitalization, increased risk of complications, potential need for dialysis and increased mortality rate [ [2] Maliborski A. Zukowski P. Nowicki G. Bogusławska R. Contrast-induced nephropathy—a review of current literature and guidelines. Med Sci Monit. 2011; 17: RA199-RA204 Crossref PubMed Scopus (35) Google Scholar ]. Reduction of contrast volume, the key risk factor for CIN, is the most effective way for CIN prevention [ [3] Cigarroa R.G. Lange R.A. Williams R.H. Hillis L.D. Dosing of contrast material to prevent contrast nephropathy in patients with renal disease. Am J Med. 1989; 86: 649-652 Abstract Full Text PDF PubMed Scopus (432) Google Scholar ]. Previous studies [ 4 Tatsugami F. Matsuki M. Nakai G. et al. Body size-adapted dose of contrast material and scanning protocol in 320-detector row CT coronary angiography. J Comput Assist Tomogr. 2011; 35: 475-479 Crossref PubMed Scopus (6) Google Scholar , 5 Tatsugami F. Matsuki M. Inada Y. et al. Feasibility of low-volume injections of contrast material with a body weight-adapted iodine-dose protocol in 320-detector row coronary CT angiography. Acad Radiol. 2010; 17: 207-211 Abstract Full Text Full Text PDF PubMed Scopus (43) Google Scholar ] have confirmed the feasibility of contrast material volume reduction with a body weight (BW)-adapted iodine-dose protocol in 320-slice coronary CTA. However, excessive contrast material may inadvertently be given in heavier patients when the dose is determined by BW only. Study showed that body mass index (BMI) has a positive linear influence on arterial attenuation with fixed iodine per BW [ [6] Zhu X. Zhu Y. Xu H. Yang G. Tang L. Xu Y. Dual-source CT coronary angiography involving injection protocol with iodine load tailored to patient body weight and body mass index: estimation of optimal contrast material dose. Acta Radiol. 2013; 54: 149-155 Crossref PubMed Scopus (11) Google Scholar ]. So, it is reasonable to establish an individualized contrast volume protocol adapted to BMI. This study aims to evaluate retrospectively whether reduction in contrast volume adapted to BMI affects the diagnostic accuracy of 320-slice CTA, with ICA as the reference standard." @default.
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• W2032931168 date "2014-03-01" @default.
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• W2032931168 title "Contrast volume reduction adapted to body mass index for 320-slice coronary computed tomography angiography: Results from four-year clinical routine at a single center" @default.
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