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- W2032935570 abstract "Three series of N-Mannich bases of 3,4-dihydropyrimidine-2(1H)-ones(DHPMs) 7a-g, 8a-g, and 9a-g have been prepared by Mannich reaction of DHPMs 4a-c with seven different heterocyclic secondary amino compounds 6a-g and formaldehyde 5. The precursors DHPMs 4a-c have been derived by a Biginelli reaction of three aromatic aldehydes 1a-c with ethylacetoacetate 2 and urea 3. The chemical structure of all the three series of N-Mannich bases have been elucidated by elemental analysis and spectral studies (IR, H and C NMR). They have been assayed in vitro for their biological activity against E. coli and B. subtilis bacterial species and A. niger and C. albicans fungal microorganisms." @default.
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- W2032935570 date "2009-06-16" @default.
- W2032935570 modified "2023-09-26" @default.
- W2032935570 title "ChemInform Abstract: Synthesis and in vitro Study of Biological Activity of Heterocyclic N-Mannich Bases." @default.
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- W2032935570 doi "https://doi.org/10.1002/chin.200924160" @default.
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