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• W2032938403 abstract "Abstract Background Studies reported unintended pleiotropic effects for a number of pesticidal proteins ectopically expressed in transgenic crops, but the nature and significance of such effects in planta remain poorly understood. Here we assessed the effects of corn cystatin II (CCII), a potent inhibitor of C1A cysteine (Cys) proteases considered for insect and pathogen control, on the leaf proteome and pathogen resistance status of potato lines constitutively expressing this protein. Results The leaf proteome of lines accumulating CCII at different levels was resolved by 2-dimensional gel electrophoresis and compared with the leaf proteome of a control (parental) line. Out of ca. 700 proteins monitored on 2-D gels, 23 were significantly up- or downregulated in CCII-expressing leaves, including 14 proteins detected de novo or up-regulated by more than five-fold compared to the control. Most up-regulated proteins were abiotic or biotic stress-responsive proteins, including different secretory peroxidases, wound inducible protease inhibitors and pathogenesis-related proteins. Accordingly, infection of leaf tissues by the fungal necrotroph Botryris cinerea was prevented in CCII-expressing plants, despite a null impact of CCII on growth of this pathogen and the absence of extracellular Cys protease targets for the inhibitor. Conclusions These data point to the onset of pleiotropic effects altering the leaf proteome in transgenic plants expressing recombinant protease inhibitors. They also show the potential of these proteins as ectopic modulators of stress responses in planta , useful to engineer biotic or abiotic stress tolerance in crop plants of economic significance." @default.
• W2032938403 created "2016-06-24" @default.
• W2032938403 creator A5023569085 @default.
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• W2032938403 date "2012-11-01" @default.
• W2032938403 modified "2023-10-08" @default.
• W2032938403 title "Beneficial ‘unintended effects’ of a cereal cystatin in transgenic lines of potato, Solanum tuberosum" @default.
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• W2032938403 cites W1958259849 @default.
• W2032938403 cites W1964730417 @default.
• W2032938403 cites W1965015418 @default.
• W2032938403 cites W1965702707 @default.
• W2032938403 cites W1973273549 @default.
• W2032938403 cites W1978989949 @default.
• W2032938403 cites W1981427309 @default.
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• W2032938403 cites W2013156671 @default.
• W2032938403 cites W2033262167 @default.
• W2032938403 cites W2033707520 @default.
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• W2032938403 doi "https://doi.org/10.1186/1471-2229-12-198" @default.
• W2032938403 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3534561" @default.
• W2032938403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23116303" @default.
• W2032938403 hasPublicationYear "2012" @default.
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