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• W2032947564 abstract "Successful vaccines function almost exclusively by establishing long-lived plasma cells that secrete antibody into the blood and at mucosal sites. Some pathogens, such as HIV and the influenza A viruses, use a mutational strategy to escape neutralization by antibodies specific for surface glycoproteins. The CD8+ cytotoxic T–lymphocyte (CTL) response is, on the other hand, directed mostly at peptides derived from conserved, internal virus proteins. Can CTL memory be manipulated to provide cross-reactive protection?" @default.
• W2032947564 created "2016-06-24" @default.
• W2032947564 creator A5003005203 @default.
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• W2032947564 date "2009-04-29" @default.
• W2032947564 modified "2023-10-16" @default.
• W2032947564 title "Thinking About Broadly Cross-Reactive Vaccines" @default.
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• W2032947564 doi "https://doi.org/10.1038/clpt.2009.52" @default.
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