Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033003340> ?p ?o ?g. }
- W2033003340 endingPage "692" @default.
- W2033003340 startingPage "679" @default.
- W2033003340 abstract "High-risk human papillomavirus (HPV) is a causative agent for an increasing subset of oropharyngeal squamous cell carcinomas (OPSCCs), and current evidence supports these tumors as having identifiable risk factors and improved response to therapy. However, the biochemical and molecular alterations underlying the pathobiology of HPV-associated OPSCC (designated HPV(+) OPSCC) remain unclear. Herein, we profile miRNA expression patterns in HPV(+) OPSCC to provide a more detailed understanding of pathologic molecular events and to identify biomarkers that may have applicability for early diagnosis, improved staging, and prognostic stratification. Differentially expressed miRNAs were identified in RNA isolated from an initial clinical cohort of HPV(+/-) OPSCC tumors by quantitative PCR-based miRNA profiling. This oncogenic miRNA panel was validated using miRNA sequencing and clinical data from The Cancer Genome Atlas and miRNA in situ hybridization. The HPV-associated oncogenic miRNA panel has potential utility in diagnosis and disease stratification and in mechanistic elucidation of molecular factors that contribute to OPSCC development, progression, and differential response to therapy." @default.
- W2033003340 created "2016-06-24" @default.
- W2033003340 creator A5006075716 @default.
- W2033003340 creator A5007403831 @default.
- W2033003340 creator A5032803774 @default.
- W2033003340 creator A5034090671 @default.
- W2033003340 creator A5069777080 @default.
- W2033003340 creator A5072866478 @default.
- W2033003340 creator A5073848797 @default.
- W2033003340 creator A5088194830 @default.
- W2033003340 creator A5088837180 @default.
- W2033003340 date "2015-03-01" @default.
- W2033003340 modified "2023-10-14" @default.
- W2033003340 title "Identification of a Human Papillomavirus–Associated Oncogenic miRNA Panel in Human Oropharyngeal Squamous Cell Carcinoma Validated by Bioinformatics Analysis of The Cancer Genome Atlas" @default.
- W2033003340 cites W1491728704 @default.
- W2033003340 cites W1577577364 @default.
- W2033003340 cites W1969003435 @default.
- W2033003340 cites W1971855584 @default.
- W2033003340 cites W1983670437 @default.
- W2033003340 cites W1983723158 @default.
- W2033003340 cites W1985373884 @default.
- W2033003340 cites W2007980875 @default.
- W2033003340 cites W2015840556 @default.
- W2033003340 cites W2019867275 @default.
- W2033003340 cites W2020932061 @default.
- W2033003340 cites W2023778490 @default.
- W2033003340 cites W2026996973 @default.
- W2033003340 cites W2028496196 @default.
- W2033003340 cites W2033595939 @default.
- W2033003340 cites W2035213975 @default.
- W2033003340 cites W2037275886 @default.
- W2033003340 cites W2047870085 @default.
- W2033003340 cites W2050107275 @default.
- W2033003340 cites W2052599765 @default.
- W2033003340 cites W2056302937 @default.
- W2033003340 cites W2057241466 @default.
- W2033003340 cites W2060559193 @default.
- W2033003340 cites W2060763328 @default.
- W2033003340 cites W2061446835 @default.
- W2033003340 cites W2080250239 @default.
- W2033003340 cites W2085430680 @default.
- W2033003340 cites W2089786741 @default.
- W2033003340 cites W2098215107 @default.
- W2033003340 cites W2098637032 @default.
- W2033003340 cites W2105870502 @default.
- W2033003340 cites W2107283868 @default.
- W2033003340 cites W2110664940 @default.
- W2033003340 cites W2112441059 @default.
- W2033003340 cites W2119613560 @default.
- W2033003340 cites W2121629705 @default.
- W2033003340 cites W2133183695 @default.
- W2033003340 cites W2133635440 @default.
- W2033003340 cites W2136499566 @default.
- W2033003340 cites W2138934177 @default.
- W2033003340 cites W2143680521 @default.
- W2033003340 cites W2146906100 @default.
- W2033003340 cites W2148028028 @default.
- W2033003340 cites W2151868278 @default.
- W2033003340 cites W2157930304 @default.
- W2033003340 cites W2158811981 @default.
- W2033003340 cites W2160697532 @default.
- W2033003340 cites W2163453522 @default.
- W2033003340 cites W2316081269 @default.
- W2033003340 doi "https://doi.org/10.1016/j.ajpath.2014.11.018" @default.
- W2033003340 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4348472" @default.
- W2033003340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25572154" @default.
- W2033003340 hasPublicationYear "2015" @default.
- W2033003340 type Work @default.
- W2033003340 sameAs 2033003340 @default.
- W2033003340 citedByCount "43" @default.
- W2033003340 countsByYear W20330033402015 @default.
- W2033003340 countsByYear W20330033402016 @default.
- W2033003340 countsByYear W20330033402017 @default.
- W2033003340 countsByYear W20330033402018 @default.
- W2033003340 countsByYear W20330033402019 @default.
- W2033003340 countsByYear W20330033402020 @default.
- W2033003340 countsByYear W20330033402021 @default.
- W2033003340 countsByYear W20330033402022 @default.
- W2033003340 countsByYear W20330033402023 @default.
- W2033003340 crossrefType "journal-article" @default.
- W2033003340 hasAuthorship W2033003340A5006075716 @default.
- W2033003340 hasAuthorship W2033003340A5007403831 @default.
- W2033003340 hasAuthorship W2033003340A5032803774 @default.
- W2033003340 hasAuthorship W2033003340A5034090671 @default.
- W2033003340 hasAuthorship W2033003340A5069777080 @default.
- W2033003340 hasAuthorship W2033003340A5072866478 @default.
- W2033003340 hasAuthorship W2033003340A5073848797 @default.
- W2033003340 hasAuthorship W2033003340A5088194830 @default.
- W2033003340 hasAuthorship W2033003340A5088837180 @default.
- W2033003340 hasBestOaLocation W20330033401 @default.
- W2033003340 hasConcept C104317684 @default.
- W2033003340 hasConcept C121608353 @default.
- W2033003340 hasConcept C142724271 @default.
- W2033003340 hasConcept C143998085 @default.
- W2033003340 hasConcept C145059251 @default.
- W2033003340 hasConcept C150194340 @default.
- W2033003340 hasConcept C18431079 @default.
- W2033003340 hasConcept C2779134260 @default.