Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033011866> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2033011866 endingPage "A185" @default.
- W2033011866 startingPage "A185" @default.
- W2033011866 abstract "Analyses of drug cost-effectiveness have traditionally been based on two key components: effectiveness measured by clinical endpoints reported in product label or biomedical literature, and cost obtained from available pricing sources. While the former is a relatively well-defined value derived from pivotal trials and subsequent studies, the latter has often not been well-described or rigorously assessed, and may be based upon manufacturer-reported pricing information that has been shown to be inaccurate and unreliable. This study examines existing benchmarks against newly available sources of pharmaceutical pricing, describes their interrelationships and assesses their stability over time. Using publicly available cost data for wholesale acquisition cost (WAC), average manufacturer price (AMP), national average drug acquisition cost (NADAC), AMP-based federal upper limit (FUL), and a composite of six states’ average acquisition cost (AAC), mean, median, and standard deviation values were calculated for a broad range of pharmaceuticals and trade classes (brand vs. generic) and analyzed temporally for trend and consistency patterns. Available pricing data reflects an extremely high degree of variability and inconsistent relationships, both between equivalent products and from one price type to another. Generic drug prices demonstrated the greatest irregularity, and although the ratio of NADAC or AMP to WAC for branded drugs showed correlations overall, for given products those relationships could be substantially at variance. Continuing review and analysis of all available price types is needed to identify a reliable drug pricing benchmark that permits reviewers and clinicians to determine the optimal course of treatment. Since reported ratios may shift over time, future reports of cost-effectiveness must explicitly identify the cost basis employed and its reliability for the products at issue." @default.
- W2033011866 created "2016-06-24" @default.
- W2033011866 creator A5008733775 @default.
- W2033011866 creator A5068158620 @default.
- W2033011866 creator A5078955312 @default.
- W2033011866 creator A5090924843 @default.
- W2033011866 date "2014-05-01" @default.
- W2033011866 modified "2023-09-26" @default.
- W2033011866 title "In search of lost costs: The implications for cost-effectiveness research when the price isn’t right" @default.
- W2033011866 doi "https://doi.org/10.1016/j.jval.2014.03.1081" @default.
- W2033011866 hasPublicationYear "2014" @default.
- W2033011866 type Work @default.
- W2033011866 sameAs 2033011866 @default.
- W2033011866 citedByCount "0" @default.
- W2033011866 crossrefType "journal-article" @default.
- W2033011866 hasAuthorship W2033011866A5008733775 @default.
- W2033011866 hasAuthorship W2033011866A5068158620 @default.
- W2033011866 hasAuthorship W2033011866A5078955312 @default.
- W2033011866 hasAuthorship W2033011866A5090924843 @default.
- W2033011866 hasBestOaLocation W20330118661 @default.
- W2033011866 hasConcept C119857082 @default.
- W2033011866 hasConcept C127413603 @default.
- W2033011866 hasConcept C13280743 @default.
- W2033011866 hasConcept C146978453 @default.
- W2033011866 hasConcept C149782125 @default.
- W2033011866 hasConcept C154945302 @default.
- W2033011866 hasConcept C162118730 @default.
- W2033011866 hasConcept C162324750 @default.
- W2033011866 hasConcept C185798385 @default.
- W2033011866 hasConcept C204323151 @default.
- W2033011866 hasConcept C205649164 @default.
- W2033011866 hasConcept C2524010 @default.
- W2033011866 hasConcept C2776291640 @default.
- W2033011866 hasConcept C2776436953 @default.
- W2033011866 hasConcept C33923547 @default.
- W2033011866 hasConcept C41008148 @default.
- W2033011866 hasConcept C42475967 @default.
- W2033011866 hasConcept C71924100 @default.
- W2033011866 hasConcept C90673727 @default.
- W2033011866 hasConceptScore W2033011866C119857082 @default.
- W2033011866 hasConceptScore W2033011866C127413603 @default.
- W2033011866 hasConceptScore W2033011866C13280743 @default.
- W2033011866 hasConceptScore W2033011866C146978453 @default.
- W2033011866 hasConceptScore W2033011866C149782125 @default.
- W2033011866 hasConceptScore W2033011866C154945302 @default.
- W2033011866 hasConceptScore W2033011866C162118730 @default.
- W2033011866 hasConceptScore W2033011866C162324750 @default.
- W2033011866 hasConceptScore W2033011866C185798385 @default.
- W2033011866 hasConceptScore W2033011866C204323151 @default.
- W2033011866 hasConceptScore W2033011866C205649164 @default.
- W2033011866 hasConceptScore W2033011866C2524010 @default.
- W2033011866 hasConceptScore W2033011866C2776291640 @default.
- W2033011866 hasConceptScore W2033011866C2776436953 @default.
- W2033011866 hasConceptScore W2033011866C33923547 @default.
- W2033011866 hasConceptScore W2033011866C41008148 @default.
- W2033011866 hasConceptScore W2033011866C42475967 @default.
- W2033011866 hasConceptScore W2033011866C71924100 @default.
- W2033011866 hasConceptScore W2033011866C90673727 @default.
- W2033011866 hasIssue "3" @default.
- W2033011866 hasLocation W20330118661 @default.
- W2033011866 hasOpenAccess W2033011866 @default.
- W2033011866 hasPrimaryLocation W20330118661 @default.
- W2033011866 hasRelatedWork W112744582 @default.
- W2033011866 hasRelatedWork W1485630101 @default.
- W2033011866 hasRelatedWork W1677601786 @default.
- W2033011866 hasRelatedWork W2030059621 @default.
- W2033011866 hasRelatedWork W2350879319 @default.
- W2033011866 hasRelatedWork W2353865532 @default.
- W2033011866 hasRelatedWork W2498017833 @default.
- W2033011866 hasRelatedWork W2748952813 @default.
- W2033011866 hasRelatedWork W2899084033 @default.
- W2033011866 hasRelatedWork W3081841992 @default.
- W2033011866 hasVolume "17" @default.
- W2033011866 isParatext "false" @default.
- W2033011866 isRetracted "false" @default.
- W2033011866 magId "2033011866" @default.
- W2033011866 workType "article" @default.