FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033128599> ?p ?o ?g. }

• W2033128599 endingPage "855" @default.
• W2033128599 startingPage "839" @default.
• W2033128599 abstract "Diverse structural and functional brain alterations have been identified in both schizophrenia and bipolar disorder, but with variable replicability, significant overlap and often in limited number of subjects. In this paper, we aimed to clarify differences between bipolar disorder and schizophrenia by combining fMRI (collected during an auditory oddball task) and diffusion tensor imaging (DTI) data. We proposed a fusion method, multimodal CCA+ joint ICA, which increases flexibility in statistical assumptions beyond existing approaches and can achieve higher estimation accuracy. The data collected from 164 participants (62 healthy controls, 54 schizophrenia and 48 bipolar) were extracted into features (contrast maps for fMRI and fractional anisotropy (FA) for DTI) and analyzed in multiple facets to investigate the group differences for each pair-wised groups and each modality. Specifically, both patient groups shared significant dysfunction in dorsolateral prefrontal cortex and thalamus, as well as reduced white matter (WM) integrity in anterior thalamic radiation and uncinate fasciculus. Schizophrenia and bipolar subjects were separated by functional differences in medial frontal and visual cortex, as well as WM tracts associated with occipital and frontal lobes. Both patients and controls showed similar spatial distributions in motor and parietal regions, but exhibited significant variations in temporal lobe. Furthermore, there were different group trends for age effects on loading parameters in motor cortex and multiple WM regions, suggesting that brain dysfunction and WM disruptions occurred in identified regions for both disorders. Most importantly, we can visualize an underlying function-structure network by evaluating the joint components with strong links between DTI and fMRI. Our findings suggest that although the two patient groups showed several distinct brain patterns from each other and healthy controls, they also shared common abnormalities in prefrontal thalamic WM integrity and in frontal brain mechanisms." @default.
• W2033128599 created "2016-06-24" @default.
• W2033128599 creator A5011715160 @default.
• W2033128599 creator A5015647568 @default.
• W2033128599 creator A5030080051 @default.
• W2033128599 creator A5032850756 @default.
• W2033128599 creator A5060798483 @default.
• W2033128599 creator A5066292657 @default.
• W2033128599 creator A5069190537 @default.
• W2033128599 creator A5073577615 @default.
• W2033128599 date "2011-08-01" @default.
• W2033128599 modified "2023-10-16" @default.
• W2033128599 title "Discriminating schizophrenia and bipolar disorder by fusing fMRI and DTI in a multimodal CCA+ joint ICA model" @default.
• W2033128599 cites W150800720 @default.
• W2033128599 cites W1964162654 @default.
• W2033128599 cites W1973404966 @default.
• W2033128599 cites W1975802043 @default.
• W2033128599 cites W1981176642 @default.
• W2033128599 cites W1982299455 @default.
• W2033128599 cites W1984990856 @default.
• W2033128599 cites W1985316884 @default.
• W2033128599 cites W1985327120 @default.
• W2033128599 cites W1985671693 @default.
• W2033128599 cites W1986508264 @default.
• W2033128599 cites W1988196101 @default.
• W2033128599 cites W1988667314 @default.
• W2033128599 cites W1988954604 @default.
• W2033128599 cites W1993442042 @default.
• W2033128599 cites W1995907546 @default.
• W2033128599 cites W1996767160 @default.
• W2033128599 cites W1998504213 @default.
• W2033128599 cites W2000101415 @default.
• W2033128599 cites W2000133863 @default.
• W2033128599 cites W2003449088 @default.
• W2033128599 cites W2009837079 @default.
• W2033128599 cites W2012257319 @default.
• W2033128599 cites W2012351519 @default.
• W2033128599 cites W2013115634 @default.
• W2033128599 cites W2019465651 @default.
• W2033128599 cites W2023682802 @default.
• W2033128599 cites W2029990654 @default.
• W2033128599 cites W2030700120 @default.
• W2033128599 cites W2035245127 @default.
• W2033128599 cites W2040709265 @default.
• W2033128599 cites W2043196359 @default.
• W2033128599 cites W2045554669 @default.
• W2033128599 cites W2046738354 @default.
• W2033128599 cites W2053865537 @default.
• W2033128599 cites W2054764490 @default.
• W2033128599 cites W2056683249 @default.
• W2033128599 cites W2057179800 @default.
• W2033128599 cites W2059685157 @default.
• W2033128599 cites W2063237661 @default.
• W2033128599 cites W2064598115 @default.
• W2033128599 cites W2067661503 @default.
• W2033128599 cites W2078604986 @default.
• W2033128599 cites W2079450984 @default.
• W2033128599 cites W2080791044 @default.
• W2033128599 cites W2081689238 @default.
• W2033128599 cites W2082207932 @default.
• W2033128599 cites W2082641960 @default.
• W2033128599 cites W2083433785 @default.
• W2033128599 cites W2084040762 @default.
• W2033128599 cites W2088060544 @default.
• W2033128599 cites W2091177453 @default.
• W2033128599 cites W2094416046 @default.
• W2033128599 cites W2095068146 @default.
• W2033128599 cites W2096052879 @default.
• W2033128599 cites W2100602669 @default.
• W2033128599 cites W2104524472 @default.
• W2033128599 cites W2104609773 @default.
• W2033128599 cites W2108384452 @default.
• W2033128599 cites W2108878896 @default.
• W2033128599 cites W2109387154 @default.
• W2033128599 cites W2111095620 @default.
• W2033128599 cites W2111705033 @default.
• W2033128599 cites W2114614491 @default.
• W2033128599 cites W2116295973 @default.
• W2033128599 cites W2120387890 @default.
• W2033128599 cites W2124525546 @default.
• W2033128599 cites W2131436045 @default.
• W2033128599 cites W2132801576 @default.
• W2033128599 cites W2136763679 @default.
• W2033128599 cites W2137483563 @default.
• W2033128599 cites W2137911531 @default.
• W2033128599 cites W2139739917 @default.
• W2033128599 cites W2141279969 @default.
• W2033128599 cites W2142059961 @default.
• W2033128599 cites W2143090565 @default.
• W2033128599 cites W2145677204 @default.
• W2033128599 cites W2146827639 @default.
• W2033128599 cites W2149966221 @default.
• W2033128599 cites W2152179757 @default.
• W2033128599 cites W2152828783 @default.
• W2033128599 cites W2153774626 @default.
• W2033128599 cites W2154360927 @default.
• W2033128599 cites W2156294540 @default.
• W2033128599 cites W2162010696 @default.

• next