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- W2033138082 abstract "The meniscus is a crescent shaped fibrocartilage in the knee comprised of a circumferentially aligned collagenous extracellular matrix (ECM) that functions to transmit load and enhance joint stability. The meniscus ECM varies as a function of region, where the inner meniscus is comprised of 70% collagen (60% type II vs. 40% type I), while the outer meniscus contains 80% collagen (99% type I) [1]. Similarly, cells within the inner meniscus are rounder and more ‘chondrocyte-like’, while those in the outer meniscus are elongated and ‘fibroblast-like’ [2]. Injury of the meniscus alters joint loading and hastens the onset of osteoarthritis. As meniscus healing is limited, there exists a need for functional meniscus replacements." @default.
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- W2033138082 date "2012-06-20" @default.
- W2033138082 modified "2023-09-28" @default.
- W2033138082 title "Mesenchymal Stem Cell Morphology in a Fibrous Microenvironment With Length Scales Matching the Native Meniscus" @default.
- W2033138082 doi "https://doi.org/10.1115/sbc2012-80729" @default.
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