FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033189766> ?p ?o ?g. }

• W2033189766 endingPage "1672" @default.
• W2033189766 startingPage "1668" @default.
• W2033189766 abstract "OBJECTIVE To determine urinary nerve growth factor (NGF) levels in patients with overactive bladder (OAB) and after treatment with antimuscarinics. PATIENTS AND METHODS Urinary NGF levels were measured in 38 ‘normal’ controls and 70 patients with OAB. Patients were treated with tolterodine 4 mg once daily. Urinary NGF levels were measured by enzyme‐linked immunosorbent assay method and normalized by urinary creatinine levels (NGF/Cr). The urinary NGF/Cr levels and urgency severity scale (USS) were compared at baseline, 1, 2 and 3 months after antimuscarinics, and 1 month after discontinuing treatment. RESULTS The urinary NGF/Cr level was very low in normal controls with a mean ( sem ) of 0.005 (0.003). Patients with OAB had significantly higher baseline urinary NGF/Cr levels than the controls. Urinary NGF/Cr levels were significantly reduced at 3 months in 50 responders (1.10 [0.26] before vs 0.41 [0.09] after, P = 0.008) but not in the 20 non‐responders (1.38 [0.54] before vs 1.30 [0.46] after, P = 0.879). However, after discontinuing antimuscarinic treatment for 1 month, the urinary NGF/Cr level was elevated in 23 responders at 0.83 (0.33) and in five non‐responders at 2.72 (1.41). The USS scores significantly changed with the change of urinary NGF/Cr levels in responders at different time points. The voided volume increased but maximum urinary flow rate and postvoid residual volume did not increase in responders after 3‐months of antimuscarinic treatment. The limitation of this study was the lack of a control arm for comparison. CONCLUSIONS Changes in the urinary NGF levels were associated with the changes of the USS scores after antimuscarinic treatment and discontinued medication. The urinary NGF level could be a potential biomarker for evaluating therapeutic results of antimuscarinics therapy." @default.
• W2033189766 created "2016-06-24" @default.
• W2033189766 creator A5053694613 @default.
• W2033189766 creator A5064972271 @default.
• W2033189766 creator A5076037136 @default.
• W2033189766 date "2009-05-27" @default.
• W2033189766 modified "2023-10-17" @default.
• W2033189766 title "Decrease of urinary nerve growth factor levels after antimuscarinic therapy in patients with overactive bladder" @default.
• W2033189766 cites W1967312126 @default.
• W2033189766 cites W1973849826 @default.
• W2033189766 cites W1987343995 @default.
• W2033189766 cites W1989637542 @default.
• W2033189766 cites W2000807287 @default.
• W2033189766 cites W2015656030 @default.
• W2033189766 cites W2028257278 @default.
• W2033189766 cites W2031978047 @default.
• W2033189766 cites W2033847316 @default.
• W2033189766 cites W2034050469 @default.
• W2033189766 cites W2042125279 @default.
• W2033189766 cites W2072658132 @default.
• W2033189766 cites W2076400201 @default.
• W2033189766 cites W2108836444 @default.
• W2033189766 cites W2122687066 @default.
• W2033189766 cites W2143561995 @default.
• W2033189766 cites W2162916526 @default.
• W2033189766 doi "https://doi.org/10.1111/j.1464-410x.2009.08380.x" @default.
• W2033189766 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19220267" @default.
• W2033189766 hasPublicationYear "2009" @default.
• W2033189766 type Work @default.
• W2033189766 sameAs 2033189766 @default.
• W2033189766 citedByCount "97" @default.
• W2033189766 countsByYear W20331897662012 @default.
• W2033189766 countsByYear W20331897662013 @default.
• W2033189766 countsByYear W20331897662014 @default.
• W2033189766 countsByYear W20331897662015 @default.
• W2033189766 countsByYear W20331897662016 @default.
• W2033189766 countsByYear W20331897662017 @default.
• W2033189766 countsByYear W20331897662018 @default.
• W2033189766 countsByYear W20331897662019 @default.
• W2033189766 countsByYear W20331897662020 @default.
• W2033189766 countsByYear W20331897662021 @default.
• W2033189766 countsByYear W20331897662022 @default.
• W2033189766 countsByYear W20331897662023 @default.
• W2033189766 crossrefType "journal-article" @default.
• W2033189766 hasAuthorship W2033189766A5053694613 @default.
• W2033189766 hasAuthorship W2033189766A5064972271 @default.
• W2033189766 hasAuthorship W2033189766A5076037136 @default.
• W2033189766 hasConcept C126322002 @default.
• W2033189766 hasConcept C126894567 @default.
• W2033189766 hasConcept C134018914 @default.
• W2033189766 hasConcept C142724271 @default.
• W2033189766 hasConcept C170493617 @default.
• W2033189766 hasConcept C204787440 @default.
• W2033189766 hasConcept C2778423431 @default.
• W2033189766 hasConcept C2778941218 @default.
• W2033189766 hasConcept C2779762690 @default.
• W2033189766 hasConcept C2781020410 @default.
• W2033189766 hasConcept C71924100 @default.
• W2033189766 hasConcept C77411442 @default.
• W2033189766 hasConceptScore W2033189766C126322002 @default.
• W2033189766 hasConceptScore W2033189766C126894567 @default.
• W2033189766 hasConceptScore W2033189766C134018914 @default.
• W2033189766 hasConceptScore W2033189766C142724271 @default.
• W2033189766 hasConceptScore W2033189766C170493617 @default.
• W2033189766 hasConceptScore W2033189766C204787440 @default.
• W2033189766 hasConceptScore W2033189766C2778423431 @default.
• W2033189766 hasConceptScore W2033189766C2778941218 @default.
• W2033189766 hasConceptScore W2033189766C2779762690 @default.
• W2033189766 hasConceptScore W2033189766C2781020410 @default.
• W2033189766 hasConceptScore W2033189766C71924100 @default.
• W2033189766 hasConceptScore W2033189766C77411442 @default.
• W2033189766 hasIssue "12" @default.
• W2033189766 hasLocation W20331897661 @default.
• W2033189766 hasLocation W20331897662 @default.
• W2033189766 hasOpenAccess W2033189766 @default.
• W2033189766 hasPrimaryLocation W20331897661 @default.
• W2033189766 hasRelatedWork W1983371621 @default.
• W2033189766 hasRelatedWork W1983573081 @default.
• W2033189766 hasRelatedWork W1996534025 @default.
• W2033189766 hasRelatedWork W2001645992 @default.
• W2033189766 hasRelatedWork W2019380449 @default.
• W2033189766 hasRelatedWork W2050061619 @default.
• W2033189766 hasRelatedWork W2065591897 @default.
• W2033189766 hasRelatedWork W2084288786 @default.
• W2033189766 hasRelatedWork W2089437227 @default.
• W2033189766 hasRelatedWork W2341135423 @default.
• W2033189766 hasVolume "103" @default.
• W2033189766 isParatext "false" @default.
• W2033189766 isRetracted "false" @default.
• W2033189766 magId "2033189766" @default.
• W2033189766 workType "article" @default.