FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033196693> ?p ?o ?g. }

• W2033196693 endingPage "107" @default.
• W2033196693 startingPage "101" @default.
• W2033196693 abstract "Abstract A prospective, randomized study to evaluate the clinical benefit of increasing the osmotic load of the hypertonic solution administered for the treatment of refractory intracranial hypertension episodes in patients with severe head injury. 25 patients with severe head injury and persistent coma, admitted in a Neurocritical Care Unit of a Tertiary Care Hospital, who required infusions of osmotic agents to treat episodes of intracranial hypertension resistant to well defined standard modes of therapy were randomly allocated to one of the two groups to receive isovolume infusions of either 7.5% hypertonic saline solution; HS [2400 mOsm/kg H2O] or 20% mannitol [1160 mOsm/kg of H2O] given 2ml/kg of either solution, i.e. 331.5 +/− 35.4 mOsm of hypertonic saline or 174.2 +/− 18 mOsm of mannitol per infusion. The variables recorded in the study were the duration and number of episodes of intracranial hypertension per day during the study period, which was stopped after the last episode of intracranial hypertension was recorded from intracranial pressure recording or after the allocated treatment failure. Patients of HS group were monitored for 7 +/− 6 days and those in the mannitol group for 8 +/− 5 days [p=NS]. The rate of failure for each treatment was also evaluated which was defined as the persistence of intracranial hypertension despite the two successive infusions of the same osmotic agent. The mean number of osmotic solute infusions was 3.4 +/− 4.5 in the HS group and 3.8 +/− 5.1 in mannitol group p=NS]. The mean number [7.1+/-2.9 vs. 14.6+/−3.4] of episodes of intracranial hypertension per day and the duration of such episode [62.6+/−28.1 vs. 93.4+/−37.2 min] was also significantly lower in the HS group [p<0.05]. The numbers of treatment failures were significantly lower in HS group: 1 out of 14 patients vs. 6 out of 11 patients [p<0.01]. In this study we have found that in patients with severe head injury requiring treatment with hypertonic solute for refractory intracranial hypertension, 2ml/kg body weight of 7.5% HS [356 +/− 14 mOsm] was more effective than giving 2ml/kg 20% mannitol [178 +/− 11mOsm]. Within the limitations of present study, the collected data suggest that giving 2ml/kg HS solution is an effective and safe initial treatment for intracranial hypertension episodes in head injury patients when there is indication of osmotherapy." @default.
• W2033196693 created "2016-06-24" @default.
• W2033196693 creator A5005694530 @default.
• W2033196693 creator A5022850674 @default.
• W2033196693 creator A5023412649 @default.
• W2033196693 creator A5032799180 @default.
• W2033196693 creator A5055636402 @default.
• W2033196693 creator A5090242576 @default.
• W2033196693 date "2007-12-01" @default.
• W2033196693 modified "2023-09-27" @default.
• W2033196693 title "Efficacy of different hypertonic solutes in the treatment of refractory intracranial hypertension in severe head injury patients: A comparative study of 2ml/kg 7.5% hypertonic saline and 2ml/kg 20% mannitol" @default.
• W2033196693 cites W1559086119 @default.
• W2033196693 cites W1916974964 @default.
• W2033196693 cites W195694324 @default.
• W2033196693 cites W1966785719 @default.
• W2033196693 cites W1978531051 @default.
• W2033196693 cites W1990285030 @default.
• W2033196693 cites W1995340300 @default.
• W2033196693 cites W2023673240 @default.
• W2033196693 cites W2029165230 @default.
• W2033196693 cites W2030056476 @default.
• W2033196693 cites W2030692486 @default.
• W2033196693 cites W2033096785 @default.
• W2033196693 cites W2033997018 @default.
• W2033196693 cites W2039977066 @default.
• W2033196693 cites W2041266085 @default.
• W2033196693 cites W2048281702 @default.
• W2033196693 cites W2050099186 @default.
• W2033196693 cites W2051224588 @default.
• W2033196693 cites W2051280968 @default.
• W2033196693 cites W2055904172 @default.
• W2033196693 cites W2060401618 @default.
• W2033196693 cites W2066103257 @default.
• W2033196693 cites W2067151487 @default.
• W2033196693 cites W2070733220 @default.
• W2033196693 cites W2078761715 @default.
• W2033196693 cites W2084822006 @default.
• W2033196693 cites W2086954316 @default.
• W2033196693 cites W2089633088 @default.
• W2033196693 cites W2103638565 @default.
• W2033196693 cites W2136392104 @default.
• W2033196693 cites W2312658974 @default.
• W2033196693 cites W2501691840 @default.
• W2033196693 cites W4243435969 @default.
• W2033196693 doi "https://doi.org/10.1016/s0973-0508(07)80023-2" @default.
• W2033196693 hasPublicationYear "2007" @default.
• W2033196693 type Work @default.
• W2033196693 sameAs 2033196693 @default.
• W2033196693 citedByCount "4" @default.
• W2033196693 countsByYear W20331966932012 @default.
• W2033196693 countsByYear W20331966932020 @default.
• W2033196693 crossrefType "journal-article" @default.
• W2033196693 hasAuthorship W2033196693A5005694530 @default.
• W2033196693 hasAuthorship W2033196693A5022850674 @default.
• W2033196693 hasAuthorship W2033196693A5023412649 @default.
• W2033196693 hasAuthorship W2033196693A5032799180 @default.
• W2033196693 hasAuthorship W2033196693A5055636402 @default.
• W2033196693 hasAuthorship W2033196693A5090242576 @default.
• W2033196693 hasConcept C117277713 @default.
• W2033196693 hasConcept C126322002 @default.
• W2033196693 hasConcept C141071460 @default.
• W2033196693 hasConcept C14705128 @default.
• W2033196693 hasConcept C165455791 @default.
• W2033196693 hasConcept C178790620 @default.
• W2033196693 hasConcept C185592680 @default.
• W2033196693 hasConcept C2777397205 @default.
• W2033196693 hasConcept C2777975874 @default.
• W2033196693 hasConcept C2778445172 @default.
• W2033196693 hasConcept C2780954326 @default.
• W2033196693 hasConcept C3017567848 @default.
• W2033196693 hasConcept C42219234 @default.
• W2033196693 hasConcept C71924100 @default.
• W2033196693 hasConceptScore W2033196693C117277713 @default.
• W2033196693 hasConceptScore W2033196693C126322002 @default.
• W2033196693 hasConceptScore W2033196693C141071460 @default.
• W2033196693 hasConceptScore W2033196693C14705128 @default.
• W2033196693 hasConceptScore W2033196693C165455791 @default.
• W2033196693 hasConceptScore W2033196693C178790620 @default.
• W2033196693 hasConceptScore W2033196693C185592680 @default.
• W2033196693 hasConceptScore W2033196693C2777397205 @default.
• W2033196693 hasConceptScore W2033196693C2777975874 @default.
• W2033196693 hasConceptScore W2033196693C2778445172 @default.
• W2033196693 hasConceptScore W2033196693C2780954326 @default.
• W2033196693 hasConceptScore W2033196693C3017567848 @default.
• W2033196693 hasConceptScore W2033196693C42219234 @default.
• W2033196693 hasConceptScore W2033196693C71924100 @default.
• W2033196693 hasIssue "02" @default.
• W2033196693 hasLocation W20331966931 @default.
• W2033196693 hasOpenAccess W2033196693 @default.
• W2033196693 hasPrimaryLocation W20331966931 @default.
• W2033196693 hasRelatedWork W1573575187 @default.
• W2033196693 hasRelatedWork W2029961303 @default.
• W2033196693 hasRelatedWork W2030692486 @default.
• W2033196693 hasRelatedWork W2033196693 @default.
• W2033196693 hasRelatedWork W2354287136 @default.
• W2033196693 hasRelatedWork W2376845367 @default.
• W2033196693 hasRelatedWork W2382361545 @default.
• W2033196693 hasRelatedWork W2387001640 @default.

• next