FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033360938> ?p ?o ?g. }

• W2033360938 endingPage "84" @default.
• W2033360938 startingPage "80" @default.
• W2033360938 abstract "Although the pathogenetic mechanisms driving Alzheimer's disease (AD) are unclear, genetic variations may play an important role. Previous studies have identified that single nucleotide polymorphisms (SNPs) in the sortilin-related receptor, L (DLR class) A repeats containing (SORL1) gene are associated with AD or amnestic mild cognitive impairment (aMCI) patients. However, the association of SORL1 variants with AD or aMCI susceptibility in the Han Chinese population has not been adequately reported. Thus, we conducted a case-control study in 106 sporadic AD patients, 67 aMCI patients, and 179 healthy control Han Chinese subjects to determine whether SORL1 genetic variations alter the risk for AD or aMCI. Using the LDR–PCR method to genotype five polymorphisms in SORL1, we found significant associations (for AD: OR = 1.968, 95% CI = 1.273–3.042; for aMCI: OR = 2.210, 95% CI = 1.353–3.610) between the ‘A’ allele of the SORL1 SNP rs985421 and AD and aMCI, which may represent an ApoE ɛ4-independent risk factor for SAD. These findings suggest that the SORL1 SNP rs985421 may alter the risk for sporadic AD and aMCI in the Han Chinese population." @default.
• W2033360938 created "2016-06-24" @default.
• W2033360938 creator A5000563498 @default.
• W2033360938 creator A5002816081 @default.
• W2033360938 creator A5019546042 @default.
• W2033360938 creator A5036232375 @default.
• W2033360938 creator A5037400952 @default.
• W2033360938 creator A5042071097 @default.
• W2033360938 creator A5046174386 @default.
• W2033360938 creator A5046986644 @default.
• W2033360938 creator A5048301510 @default.
• W2033360938 creator A5055690600 @default.
• W2033360938 creator A5075596275 @default.
• W2033360938 creator A5081606775 @default.
• W2033360938 creator A5084027644 @default.
• W2033360938 creator A5086798264 @default.
• W2033360938 creator A5087646382 @default.
• W2033360938 creator A5090606294 @default.
• W2033360938 date "2014-03-01" @default.
• W2033360938 modified "2023-10-16" @default.
• W2033360938 title "The SORL1 polymorphism rs985421 may confer the risk for amnestic mild cognitive impairment and Alzheimer's disease in the Han Chinese population" @default.
• W2033360938 cites W1496340369 @default.
• W2033360938 cites W1970082506 @default.
• W2033360938 cites W1996675875 @default.
• W2033360938 cites W1999575197 @default.
• W2033360938 cites W2016590297 @default.
• W2033360938 cites W2018342879 @default.
• W2033360938 cites W2029353665 @default.
• W2033360938 cites W2041656884 @default.
• W2033360938 cites W2047460773 @default.
• W2033360938 cites W2058880763 @default.
• W2033360938 cites W2062533292 @default.
• W2033360938 cites W2087484885 @default.
• W2033360938 cites W2091396330 @default.
• W2033360938 cites W2098665843 @default.
• W2033360938 cites W2113708991 @default.
• W2033360938 cites W2119487442 @default.
• W2033360938 cites W2159122349 @default.
• W2033360938 cites W2162922019 @default.
• W2033360938 cites W4233829850 @default.
• W2033360938 doi "https://doi.org/10.1016/j.neulet.2014.01.029" @default.
• W2033360938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24486888" @default.
• W2033360938 hasPublicationYear "2014" @default.
• W2033360938 type Work @default.
• W2033360938 sameAs 2033360938 @default.
• W2033360938 citedByCount "16" @default.
• W2033360938 countsByYear W20333609382014 @default.
• W2033360938 countsByYear W20333609382015 @default.
• W2033360938 countsByYear W20333609382016 @default.
• W2033360938 countsByYear W20333609382018 @default.
• W2033360938 countsByYear W20333609382019 @default.
• W2033360938 countsByYear W20333609382021 @default.
• W2033360938 crossrefType "journal-article" @default.
• W2033360938 hasAuthorship W2033360938A5000563498 @default.
• W2033360938 hasAuthorship W2033360938A5002816081 @default.
• W2033360938 hasAuthorship W2033360938A5019546042 @default.
• W2033360938 hasAuthorship W2033360938A5036232375 @default.
• W2033360938 hasAuthorship W2033360938A5037400952 @default.
• W2033360938 hasAuthorship W2033360938A5042071097 @default.
• W2033360938 hasAuthorship W2033360938A5046174386 @default.
• W2033360938 hasAuthorship W2033360938A5046986644 @default.
• W2033360938 hasAuthorship W2033360938A5048301510 @default.
• W2033360938 hasAuthorship W2033360938A5055690600 @default.
• W2033360938 hasAuthorship W2033360938A5075596275 @default.
• W2033360938 hasAuthorship W2033360938A5081606775 @default.
• W2033360938 hasAuthorship W2033360938A5084027644 @default.
• W2033360938 hasAuthorship W2033360938A5086798264 @default.
• W2033360938 hasAuthorship W2033360938A5087646382 @default.
• W2033360938 hasAuthorship W2033360938A5090606294 @default.
• W2033360938 hasConcept C104317684 @default.
• W2033360938 hasConcept C126322002 @default.
• W2033360938 hasConcept C135763542 @default.
• W2033360938 hasConcept C139275648 @default.
• W2033360938 hasConcept C146304588 @default.
• W2033360938 hasConcept C153209595 @default.
• W2033360938 hasConcept C180754005 @default.
• W2033360938 hasConcept C2779134260 @default.
• W2033360938 hasConcept C2908647359 @default.
• W2033360938 hasConcept C502032728 @default.
• W2033360938 hasConcept C54355233 @default.
• W2033360938 hasConcept C57089818 @default.
• W2033360938 hasConcept C71924100 @default.
• W2033360938 hasConcept C86803240 @default.
• W2033360938 hasConcept C99454951 @default.
• W2033360938 hasConceptScore W2033360938C104317684 @default.
• W2033360938 hasConceptScore W2033360938C126322002 @default.
• W2033360938 hasConceptScore W2033360938C135763542 @default.
• W2033360938 hasConceptScore W2033360938C139275648 @default.
• W2033360938 hasConceptScore W2033360938C146304588 @default.
• W2033360938 hasConceptScore W2033360938C153209595 @default.
• W2033360938 hasConceptScore W2033360938C180754005 @default.
• W2033360938 hasConceptScore W2033360938C2779134260 @default.
• W2033360938 hasConceptScore W2033360938C2908647359 @default.
• W2033360938 hasConceptScore W2033360938C502032728 @default.
• W2033360938 hasConceptScore W2033360938C54355233 @default.
• W2033360938 hasConceptScore W2033360938C57089818 @default.
• W2033360938 hasConceptScore W2033360938C71924100 @default.
• W2033360938 hasConceptScore W2033360938C86803240 @default.

• next