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- W2033387029 abstract "—Putrescine, spermidine, spermine, RNA, DNA and protein concentrations were determined in 14 parts of the rat nervous system. If the concentrations are expressed in DNA units, putrescine and spermidine concentrations change concomitantly in the different brain parts, with the exception of hypothalamus, where relatively higher putrescine than spermidine concentrations are observed. The constancy of putrescine/spermidine ratios indicates the value of putrescine concentration as an index of spermidine biosynthesis. Spermidine correlates with RNA, except in medulla, spinal cord and peripheral nerves. It is assumed that the relative excess of spermidine in these structures indicates an additional functional role. Spermine/DNA ratios are remarkably constant in the diencephalic and telencephalic regions; they are also nearly constant, but significantly lower in midbrain, medulla, spinal cord and cerebellum. This observation gives additional support for the preferential interrelation of spermidine with RNA and spermine with DNA; i.e. for different functional roles of these two narrowly related polycations." @default.
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- W2033387029 date "1975-04-01" @default.
- W2033387029 modified "2023-09-26" @default.
- W2033387029 title "REGIONAL DISTRIBUTION OF PUTRESCINE, SPERMIDINE AND SPERMINE IN RELATION TO THE DISTRIBUTION OF RNA AND DNA IN THE RAT NERVOUS SYSTEM" @default.
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- W2033387029 doi "https://doi.org/10.1111/j.1471-4159.1975.tb03866.x" @default.
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