Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033410010> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2033410010 endingPage "221" @default.
- W2033410010 startingPage "218" @default.
- W2033410010 abstract "Rat abdominal skin flaps were subjected to total venous occlusion for 8 h. Five minutes before release of the vascular occlusion, mannitol, mannitol plus anisodamin, anisodamin or placebo (0.9% normal saline) was administered intravenously. Drug treated flaps showed a statistically significant increase in the proportion of area surviving (P < 0.001). The combination of mannitol and anisodamin was not more effective than either agent alone in increasing the proportion of area surviving. The results of biochemical analyses indicated that neither mannitol nor anisodamin affected xanthine oxidase activity (p > 0.05) but that both agents significantly reduced the increase of malondialdehyde (MDA) concentration caused by ischaemia-reperfusion (p < 0.01). Treatment with mannitol or anisodamin also prevented the increase of lactate and water content and the decrease in glucose content in the island skin flap tissue which occurred on reperfusion. The data indicate that mannitol and/or anisodamin have the potential to salvage anticipated flap necrosis. It is possible that the mechanism of action is inhibition of damage caused by toxic oxygen species and improvement in capillary reperfusion." @default.
- W2033410010 created "2016-06-24" @default.
- W2033410010 creator A5047695454 @default.
- W2033410010 creator A5067982858 @default.
- W2033410010 date "1995-01-01" @default.
- W2033410010 modified "2023-09-27" @default.
- W2033410010 title "The effect of mannitol and anisodamin on the prevention of free radical injury to post-ischaemia flaps: an experimental study" @default.
- W2033410010 cites W132686822 @default.
- W2033410010 cites W1977730483 @default.
- W2033410010 cites W2004099545 @default.
- W2033410010 cites W2027241768 @default.
- W2033410010 cites W2029297022 @default.
- W2033410010 cites W2039793575 @default.
- W2033410010 cites W2054392208 @default.
- W2033410010 cites W2061826995 @default.
- W2033410010 cites W2064482845 @default.
- W2033410010 cites W2076197577 @default.
- W2033410010 cites W2142664592 @default.
- W2033410010 cites W2158288248 @default.
- W2033410010 cites W2318054838 @default.
- W2033410010 cites W2397417152 @default.
- W2033410010 cites W2410236179 @default.
- W2033410010 cites W2413638599 @default.
- W2033410010 cites W2746384741 @default.
- W2033410010 doi "https://doi.org/10.1016/0007-1226(95)90005-5" @default.
- W2033410010 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7640854" @default.
- W2033410010 hasPublicationYear "1995" @default.
- W2033410010 type Work @default.
- W2033410010 sameAs 2033410010 @default.
- W2033410010 citedByCount "10" @default.
- W2033410010 countsByYear W20334100102014 @default.
- W2033410010 crossrefType "journal-article" @default.
- W2033410010 hasAuthorship W2033410010A5047695454 @default.
- W2033410010 hasAuthorship W2033410010A5067982858 @default.
- W2033410010 hasBestOaLocation W20334100101 @default.
- W2033410010 hasConcept C126322002 @default.
- W2033410010 hasConcept C141071460 @default.
- W2033410010 hasConcept C181199279 @default.
- W2033410010 hasConcept C185592680 @default.
- W2033410010 hasConcept C2776151105 @default.
- W2033410010 hasConcept C2777397205 @default.
- W2033410010 hasConcept C2777858674 @default.
- W2033410010 hasConcept C2778102346 @default.
- W2033410010 hasConcept C2778401633 @default.
- W2033410010 hasConcept C2778445172 @default.
- W2033410010 hasConcept C42219234 @default.
- W2033410010 hasConcept C541997718 @default.
- W2033410010 hasConcept C55493867 @default.
- W2033410010 hasConcept C71924100 @default.
- W2033410010 hasConcept C98274493 @default.
- W2033410010 hasConceptScore W2033410010C126322002 @default.
- W2033410010 hasConceptScore W2033410010C141071460 @default.
- W2033410010 hasConceptScore W2033410010C181199279 @default.
- W2033410010 hasConceptScore W2033410010C185592680 @default.
- W2033410010 hasConceptScore W2033410010C2776151105 @default.
- W2033410010 hasConceptScore W2033410010C2777397205 @default.
- W2033410010 hasConceptScore W2033410010C2777858674 @default.
- W2033410010 hasConceptScore W2033410010C2778102346 @default.
- W2033410010 hasConceptScore W2033410010C2778401633 @default.
- W2033410010 hasConceptScore W2033410010C2778445172 @default.
- W2033410010 hasConceptScore W2033410010C42219234 @default.
- W2033410010 hasConceptScore W2033410010C541997718 @default.
- W2033410010 hasConceptScore W2033410010C55493867 @default.
- W2033410010 hasConceptScore W2033410010C71924100 @default.
- W2033410010 hasConceptScore W2033410010C98274493 @default.
- W2033410010 hasIssue "4" @default.
- W2033410010 hasLocation W20334100101 @default.
- W2033410010 hasLocation W20334100102 @default.
- W2033410010 hasOpenAccess W2033410010 @default.
- W2033410010 hasPrimaryLocation W20334100101 @default.
- W2033410010 hasRelatedWork W2003938723 @default.
- W2033410010 hasRelatedWork W2033410010 @default.
- W2033410010 hasRelatedWork W2047967234 @default.
- W2033410010 hasRelatedWork W2088795026 @default.
- W2033410010 hasRelatedWork W2118496982 @default.
- W2033410010 hasRelatedWork W2324858840 @default.
- W2033410010 hasRelatedWork W2393970695 @default.
- W2033410010 hasRelatedWork W2439875401 @default.
- W2033410010 hasRelatedWork W4238867864 @default.
- W2033410010 hasRelatedWork W2525756941 @default.
- W2033410010 hasVolume "48" @default.
- W2033410010 isParatext "false" @default.
- W2033410010 isRetracted "false" @default.
- W2033410010 magId "2033410010" @default.
- W2033410010 workType "article" @default.