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- W2033417059 endingPage "56" @default.
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- W2033417059 abstract "The tripartite motif containing (TRIM) proteins are a family of proteins that have been implicated in many biological processes including cell differentiation, apoptosis, transcriptional regulation and signaling pathways. Many TRIM proteins are upregulated by the immunologically important Type I and Type II interferons and several, including TRIM5α and TRIM19/PML, restrict viral replication. There is growing evidence that TRIMs also play an important role in the broader immune response through regulating signaling pathways such as the RIG-I pathway. In this review we discuss recent research elucidating TRIM regulation of a number of pathways important in immunity and review the latest findings relating to viral restriction by TRIMs." @default.
- W2033417059 created "2016-06-24" @default.
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- W2033417059 creator A5038895852 @default.
- W2033417059 creator A5047630494 @default.
- W2033417059 date "2011-02-01" @default.
- W2033417059 modified "2023-10-17" @default.
- W2033417059 title "Tripartite-motif proteins and innate immune regulation" @default.
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- W2033417059 doi "https://doi.org/10.1016/j.coi.2010.10.021" @default.
- W2033417059 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21131187" @default.
- W2033417059 hasPublicationYear "2011" @default.
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