FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033428498> ?p ?o ?g. }

• W2033428498 endingPage "12" @default.
• W2033428498 startingPage "9" @default.
• W2033428498 abstract "Both kinesin and Rep face a similar problem—how to stay tightly associated with a linear polymer while still translocating rapidly and unidirectionally along it. While they have quite different structures and operate on different polymers, these enzymes appear to have evolved similar solutions to this problem. Both appear to use mechanisms in which one of the subunits of the dimer is tightly bound to the lattice while the second subunit moves forward to the next binding site. The two subunits then exchange identities and the process is repeated for further steps. The physical and biochemical evidence supporting this mechanism is convincing, but many important details remain to be deciphered. Importantly, the physical mechanism by which ATP hydrolysis is converted into forward motion and the nature of the intermediate in which the two subunits bind to the polymer and exchange identities are both poorly understood. It is likely that many other oligomeric motors operate using similar mechanisms, so understanding kinesin and Rep will hopefully provide molecular insight into many forms of intracellular motility." @default.
• W2033428498 created "2016-06-24" @default.
• W2033428498 creator A5005112936 @default.
• W2033428498 creator A5017864586 @default.
• W2033428498 creator A5091261902 @default.
• W2033428498 date "1998-04-01" @default.
• W2033428498 modified "2023-10-16" @default.
• W2033428498 title "Staying on Track: Common Features of DNA Helicases and Microtubule Motors" @default.
• W2033428498 cites W1525549859 @default.
• W2033428498 cites W1963863239 @default.
• W2033428498 cites W1967609633 @default.
• W2033428498 cites W1969965681 @default.
• W2033428498 cites W1976612957 @default.
• W2033428498 cites W1976626323 @default.
• W2033428498 cites W2026566036 @default.
• W2033428498 cites W2026628085 @default.
• W2033428498 cites W2043447781 @default.
• W2033428498 cites W2043849677 @default.
• W2033428498 cites W2044730950 @default.
• W2033428498 cites W2045062671 @default.
• W2033428498 cites W2054875338 @default.
• W2033428498 cites W2069455207 @default.
• W2033428498 cites W2079109735 @default.
• W2033428498 cites W2135015314 @default.
• W2033428498 cites W2144368922 @default.
• W2033428498 cites W2151541959 @default.
• W2033428498 doi "https://doi.org/10.1016/s0092-8674(00)81139-3" @default.
• W2033428498 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9546385" @default.
• W2033428498 hasPublicationYear "1998" @default.
• W2033428498 type Work @default.
• W2033428498 sameAs 2033428498 @default.
• W2033428498 citedByCount "68" @default.
• W2033428498 countsByYear W20334284982013 @default.
• W2033428498 countsByYear W20334284982015 @default.
• W2033428498 countsByYear W20334284982016 @default.
• W2033428498 countsByYear W20334284982017 @default.
• W2033428498 crossrefType "journal-article" @default.
• W2033428498 hasAuthorship W2033428498A5005112936 @default.
• W2033428498 hasAuthorship W2033428498A5017864586 @default.
• W2033428498 hasAuthorship W2033428498A5091261902 @default.
• W2033428498 hasBestOaLocation W20334284981 @default.
• W2033428498 hasConcept C104292427 @default.
• W2033428498 hasConcept C104317684 @default.
• W2033428498 hasConcept C121332964 @default.
• W2033428498 hasConcept C12554922 @default.
• W2033428498 hasConcept C139425391 @default.
• W2033428498 hasConcept C141315368 @default.
• W2033428498 hasConcept C160408235 @default.
• W2033428498 hasConcept C161223559 @default.
• W2033428498 hasConcept C181199279 @default.
• W2033428498 hasConcept C20418707 @default.
• W2033428498 hasConcept C23265538 @default.
• W2033428498 hasConcept C2779546866 @default.
• W2033428498 hasConcept C46141821 @default.
• W2033428498 hasConcept C54355233 @default.
• W2033428498 hasConcept C552990157 @default.
• W2033428498 hasConcept C55493867 @default.
• W2033428498 hasConcept C59006786 @default.
• W2033428498 hasConcept C62520636 @default.
• W2033428498 hasConcept C67705224 @default.
• W2033428498 hasConcept C70721500 @default.
• W2033428498 hasConcept C86803240 @default.
• W2033428498 hasConcept C89611455 @default.
• W2033428498 hasConcept C93126451 @default.
• W2033428498 hasConcept C95444343 @default.
• W2033428498 hasConceptScore W2033428498C104292427 @default.
• W2033428498 hasConceptScore W2033428498C104317684 @default.
• W2033428498 hasConceptScore W2033428498C121332964 @default.
• W2033428498 hasConceptScore W2033428498C12554922 @default.
• W2033428498 hasConceptScore W2033428498C139425391 @default.
• W2033428498 hasConceptScore W2033428498C141315368 @default.
• W2033428498 hasConceptScore W2033428498C160408235 @default.
• W2033428498 hasConceptScore W2033428498C161223559 @default.
• W2033428498 hasConceptScore W2033428498C181199279 @default.
• W2033428498 hasConceptScore W2033428498C20418707 @default.
• W2033428498 hasConceptScore W2033428498C23265538 @default.
• W2033428498 hasConceptScore W2033428498C2779546866 @default.
• W2033428498 hasConceptScore W2033428498C46141821 @default.
• W2033428498 hasConceptScore W2033428498C54355233 @default.
• W2033428498 hasConceptScore W2033428498C552990157 @default.
• W2033428498 hasConceptScore W2033428498C55493867 @default.
• W2033428498 hasConceptScore W2033428498C59006786 @default.
• W2033428498 hasConceptScore W2033428498C62520636 @default.
• W2033428498 hasConceptScore W2033428498C67705224 @default.
• W2033428498 hasConceptScore W2033428498C70721500 @default.
• W2033428498 hasConceptScore W2033428498C86803240 @default.
• W2033428498 hasConceptScore W2033428498C89611455 @default.
• W2033428498 hasConceptScore W2033428498C93126451 @default.
• W2033428498 hasConceptScore W2033428498C95444343 @default.
• W2033428498 hasIssue "1" @default.
• W2033428498 hasLocation W20334284981 @default.
• W2033428498 hasLocation W20334284982 @default.
• W2033428498 hasOpenAccess W2033428498 @default.
• W2033428498 hasPrimaryLocation W20334284981 @default.
• W2033428498 hasRelatedWork W1964816796 @default.
• W2033428498 hasRelatedWork W1998198313 @default.
• W2033428498 hasRelatedWork W2006683232 @default.
• W2033428498 hasRelatedWork W2019156315 @default.

• next