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- W2033431456 abstract "One of the problems in achieving high quality double contrast barium meal examinations is the variability of mucosal coating by barium sulphate suspensions. Improvement in coating may be achieved by improving the barium sulphate suspension itself (Miller, 1965; Embring and Mattsson, 1968), by increasing the duration of application of barium to the gastric wall with or without the use of anticholinergics and by ensuring complete cleanliness of the stomach. Ideally the stomach should be free of fluid to prevent dilution and flocculation of barium (Hunt and Anderson, 1976). Until recently, no effective and safe method of modifying the state of the gastric mucosa itself was available. Brimblecombe et al. (1975) described a new histamine H2 receptor antagonist, cimetidine, and studies by Pounder et al. (1975) have shown that cimetidine markedly decreased both the volume and acidity of gastric juice. No untoward side effects have been reported. It seemed that as well as its applications in the treatment of duodenal ulcer, the administration of cimetidine, by decreasing gastric secretion, might improve the mucosal coating properties of barium sulphate suspensions." @default.
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- W2033431456 date "1977-06-01" @default.
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- W2033431456 title "The effect of cimetidine on barium coating of the gastric mucosa" @default.
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- W2033431456 doi "https://doi.org/10.1259/0007-1285-50-594-445" @default.
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