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- W2033435247 abstract "Selective cleavage of O2‘ and O3‘ ester groups from ribonucleoside derivatives has been accomplished with Dowex 1 × 2 (CF3CH2O-) in 2,2,2-trifluoroethanol (TFE) or lithium trifluoroethoxide/TFE. Deacylations with Li+ -OCH2CF3/TFE proceed at ambient temperature (or with mild heating) to give the 5‘-O-acyl derivatives in superior yields and higher purity than prior approaches for selective O2‘ and O3‘ ester deprotection." @default.
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- W2033435247 date "2006-03-17" @default.
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- W2033435247 title "Selective Removal of the 2‘- and 3‘-<i>O</i>-Acyl Groups from 2‘,3‘,5‘-Tri-<i>O</i>-acylribonucleoside Derivatives with Lithium Trifluoroethoxide<sup>1</sup>" @default.
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- W2033435247 doi "https://doi.org/10.1021/jo0600104" @default.
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