FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2033452013> ?p ?o ?g. }

• W2033452013 endingPage "e75686" @default.
• W2033452013 startingPage "e75686" @default.
• W2033452013 abstract "The human WBSCR22 protein was previously shown to be up-regulated in invasive breast cancer and its ectopic expression enhances tumor cell survival in the vasculature. In the current study, we show that the WBSCR22 protein is important for cell growth. Knock-down of WBSCR22 with siRNA results in slower growth of WBSCR22-depleted cells. Treatment with siWBSCR22 causes defects in the processing of pre-rRNAs and reduces the level of free 40S ribosomal subunit, suggesting that WBSCR22 is involved in ribosome small subunit biosynthesis. The human WBSCR22 partially complements the growth of WBSCR22 yeast homologue, bud23 deletion mutant suggesting that the human WBSCR22 is a functional homologue of yeast Bud23. WBSCR22 is localized throughout the cell nucleus and is not stably associated with ribosomal subunits within the cell nucleus. We also show that the WBSCR22 protein level is decreased in lymphoblastoid cell lines derived from William-Beuren Syndrome (WBS) patients compared to healthy controls. Our data suggest that the WBSCR22 protein is a ribosome biogenesis factor involved in the biosynthesis of 40S ribosomal particles in mammalian cells." @default.
• W2033452013 created "2016-06-24" @default.
• W2033452013 creator A5002650985 @default.
• W2033452013 creator A5004530659 @default.
• W2033452013 creator A5011045595 @default.
• W2033452013 creator A5012718208 @default.
• W2033452013 date "2013-09-23" @default.
• W2033452013 modified "2023-10-17" @default.
• W2033452013 title "The Human WBSCR22 Protein Is Involved in the Biogenesis of the 40S Ribosomal Subunits in Mammalian Cells" @default.
• W2033452013 cites W1587850430 @default.
• W2033452013 cites W1976558061 @default.
• W2033452013 cites W1979373680 @default.
• W2033452013 cites W1981330837 @default.
• W2033452013 cites W2002373110 @default.
• W2033452013 cites W2007364430 @default.
• W2033452013 cites W2018751664 @default.
• W2033452013 cites W2021764678 @default.
• W2033452013 cites W2027211272 @default.
• W2033452013 cites W2029130204 @default.
• W2033452013 cites W2038169765 @default.
• W2033452013 cites W2042573239 @default.
• W2033452013 cites W2043206390 @default.
• W2033452013 cites W2058904982 @default.
• W2033452013 cites W2061074033 @default.
• W2033452013 cites W2074722040 @default.
• W2033452013 cites W2075951102 @default.
• W2033452013 cites W2078466987 @default.
• W2033452013 cites W2081133503 @default.
• W2033452013 cites W2088061246 @default.
• W2033452013 cites W2089974807 @default.
• W2033452013 cites W2114433875 @default.
• W2033452013 cites W2117670891 @default.
• W2033452013 cites W2129020678 @default.
• W2033452013 cites W2148305124 @default.
• W2033452013 cites W2165374873 @default.
• W2033452013 cites W2166346311 @default.
• W2033452013 doi "https://doi.org/10.1371/journal.pone.0075686" @default.
• W2033452013 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3781059" @default.
• W2033452013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24086612" @default.
• W2033452013 hasPublicationYear "2013" @default.
• W2033452013 type Work @default.
• W2033452013 sameAs 2033452013 @default.
• W2033452013 citedByCount "45" @default.
• W2033452013 countsByYear W20334520132014 @default.
• W2033452013 countsByYear W20334520132015 @default.
• W2033452013 countsByYear W20334520132016 @default.
• W2033452013 countsByYear W20334520132017 @default.
• W2033452013 countsByYear W20334520132018 @default.
• W2033452013 countsByYear W20334520132019 @default.
• W2033452013 countsByYear W20334520132020 @default.
• W2033452013 countsByYear W20334520132021 @default.
• W2033452013 countsByYear W20334520132022 @default.
• W2033452013 countsByYear W20334520132023 @default.
• W2033452013 crossrefType "journal-article" @default.
• W2033452013 hasAuthorship W2033452013A5002650985 @default.
• W2033452013 hasAuthorship W2033452013A5004530659 @default.
• W2033452013 hasAuthorship W2033452013A5011045595 @default.
• W2033452013 hasAuthorship W2033452013A5012718208 @default.
• W2033452013 hasBestOaLocation W20334520131 @default.
• W2033452013 hasConcept C104292427 @default.
• W2033452013 hasConcept C104317684 @default.
• W2033452013 hasConcept C112755997 @default.
• W2033452013 hasConcept C129194359 @default.
• W2033452013 hasConcept C153911025 @default.
• W2033452013 hasConcept C2779419633 @default.
• W2033452013 hasConcept C301363 @default.
• W2033452013 hasConcept C3675279 @default.
• W2033452013 hasConcept C38062823 @default.
• W2033452013 hasConcept C54355233 @default.
• W2033452013 hasConcept C62112901 @default.
• W2033452013 hasConcept C67705224 @default.
• W2033452013 hasConcept C67905577 @default.
• W2033452013 hasConcept C81885089 @default.
• W2033452013 hasConcept C86803240 @default.
• W2033452013 hasConcept C88478588 @default.
• W2033452013 hasConcept C95444343 @default.
• W2033452013 hasConcept C97037327 @default.
• W2033452013 hasConceptScore W2033452013C104292427 @default.
• W2033452013 hasConceptScore W2033452013C104317684 @default.
• W2033452013 hasConceptScore W2033452013C112755997 @default.
• W2033452013 hasConceptScore W2033452013C129194359 @default.
• W2033452013 hasConceptScore W2033452013C153911025 @default.
• W2033452013 hasConceptScore W2033452013C2779419633 @default.
• W2033452013 hasConceptScore W2033452013C301363 @default.
• W2033452013 hasConceptScore W2033452013C3675279 @default.
• W2033452013 hasConceptScore W2033452013C38062823 @default.
• W2033452013 hasConceptScore W2033452013C54355233 @default.
• W2033452013 hasConceptScore W2033452013C62112901 @default.
• W2033452013 hasConceptScore W2033452013C67705224 @default.
• W2033452013 hasConceptScore W2033452013C67905577 @default.
• W2033452013 hasConceptScore W2033452013C81885089 @default.
• W2033452013 hasConceptScore W2033452013C86803240 @default.
• W2033452013 hasConceptScore W2033452013C88478588 @default.
• W2033452013 hasConceptScore W2033452013C95444343 @default.
• W2033452013 hasConceptScore W2033452013C97037327 @default.
• W2033452013 hasIssue "9" @default.
• W2033452013 hasLocation W20334520131 @default.
• W2033452013 hasLocation W20334520132 @default.

• next