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- W2033468519 startingPage "52" @default.
- W2033468519 abstract "Integral membrane proteins are central to many cellular processes and constitute approximately 50% of potential targets for novel drugs. However, the number of outer membrane proteins (OMPs) present in the public structure database is very limited due to the difficulties in determining structure with experimental methods. Therefore, discriminating OMPs from non-OMPs with computational methods is of medical importance as well as genome sequencing necessity. In this study, some sequence-derived structural and physicochemical features of proteins were incorporated with amino acid composition to discriminate OMPs from non-OMPs using support vector machines. The discrimination performance of the proposed method is evaluated on a benchmark dataset of 208 OMPs, 673 globular proteins, and 206 alpha-helical membrane proteins. A high overall accuracy of 97.8% was observed in the 5-fold cross-validation test. In addition, the current method distinguished OMPs from globular proteins and alpha-helical membrane proteins with overall accuracies of 98.2 and 96.4%, respectively. The prediction performance is superior to the state-of-the-art methods in the literature. It is anticipated that the current method might be a powerful tool for the discrimination of OMPs." @default.
- W2033468519 created "2016-06-24" @default.
- W2033468519 creator A5019829348 @default.
- W2033468519 creator A5023658180 @default.
- W2033468519 creator A5027674411 @default.
- W2033468519 creator A5047197050 @default.
- W2033468519 date "2010-03-01" @default.
- W2033468519 modified "2023-10-16" @default.
- W2033468519 title "Improving discrimination of outer membrane proteins by fusing different forms of pseudo amino acid composition" @default.
- W2033468519 cites W1550117682 @default.
- W2033468519 cites W1553786759 @default.
- W2033468519 cites W1605593725 @default.
- W2033468519 cites W1966991202 @default.
- W2033468519 cites W1969302426 @default.
- W2033468519 cites W1972475361 @default.
- W2033468519 cites W1977927254 @default.
- W2033468519 cites W1978136924 @default.
- W2033468519 cites W1979377731 @default.
- W2033468519 cites W1982276763 @default.
- W2033468519 cites W1986897081 @default.
- W2033468519 cites W1991608395 @default.
- W2033468519 cites W1992577925 @default.
- W2033468519 cites W1993346240 @default.
- W2033468519 cites W1995143646 @default.
- W2033468519 cites W1998354148 @default.
- W2033468519 cites W2001793217 @default.
- W2033468519 cites W2001808731 @default.
- W2033468519 cites W2010818132 @default.
- W2033468519 cites W2010877280 @default.
- W2033468519 cites W2021133722 @default.
- W2033468519 cites W2029580264 @default.
- W2033468519 cites W2030650052 @default.
- W2033468519 cites W2032764078 @default.
- W2033468519 cites W2036956828 @default.
- W2033468519 cites W2037032199 @default.
- W2033468519 cites W2037831301 @default.
- W2033468519 cites W2037838449 @default.
- W2033468519 cites W2038681300 @default.
- W2033468519 cites W2038773874 @default.
- W2033468519 cites W2040033996 @default.
- W2033468519 cites W2053963319 @default.
- W2033468519 cites W2063608300 @default.
- W2033468519 cites W2073718013 @default.
- W2033468519 cites W2075700253 @default.
- W2033468519 cites W2077799065 @default.
- W2033468519 cites W2080915318 @default.
- W2033468519 cites W2085277871 @default.
- W2033468519 cites W2098637030 @default.
- W2033468519 cites W2099344204 @default.
- W2033468519 cites W2102354653 @default.
- W2033468519 cites W2105255303 @default.
- W2033468519 cites W2107432340 @default.
- W2033468519 cites W2108211735 @default.
- W2033468519 cites W2108733892 @default.
- W2033468519 cites W2112227723 @default.
- W2033468519 cites W2114531694 @default.
- W2033468519 cites W2120026469 @default.
- W2033468519 cites W2122554885 @default.
- W2033468519 cites W2125879333 @default.
- W2033468519 cites W2127177253 @default.
- W2033468519 cites W2128298966 @default.
- W2033468519 cites W2128361588 @default.
- W2033468519 cites W2129838159 @default.
- W2033468519 cites W2130479394 @default.
- W2033468519 cites W2131553403 @default.
- W2033468519 cites W2132292391 @default.
- W2033468519 cites W2133650672 @default.
- W2033468519 cites W2134665553 @default.
- W2033468519 cites W2135083016 @default.
- W2033468519 cites W2136930152 @default.
- W2033468519 cites W2137565410 @default.
- W2033468519 cites W2145652776 @default.
- W2033468519 cites W2145957695 @default.
- W2033468519 cites W2146773802 @default.
- W2033468519 cites W2147826517 @default.
- W2033468519 cites W2149730127 @default.
- W2033468519 cites W2150044256 @default.
- W2033468519 cites W2154849669 @default.
- W2033468519 cites W2156125289 @default.
- W2033468519 cites W2156192813 @default.
- W2033468519 cites W2157142295 @default.
- W2033468519 cites W2160020195 @default.
- W2033468519 cites W2160072419 @default.
- W2033468519 cites W2161530105 @default.
- W2033468519 cites W2165724689 @default.
- W2033468519 cites W2167393453 @default.
- W2033468519 cites W2169317607 @default.
- W2033468519 cites W278909723 @default.
- W2033468519 cites W4249920046 @default.
- W2033468519 doi "https://doi.org/10.1016/j.ab.2009.10.040" @default.
- W2033468519 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19874797" @default.
- W2033468519 hasPublicationYear "2010" @default.
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