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- W2033492904 abstract "Article AbstractBackground: Suicidal thoughts and behaviors, also known as suicidality, are a fairly neglected area of study in patients with obsessive-compulsive disorder (OCD).Objective: To evaluate several aspects of suicidality in a large multicenter sample of OCD patients and to compare those with and without suicidal ideation, plans, and attempts according to demographic and clinical variables, including symptom dimensions and comorbid disorders.Method: This cross-sectional study included 582 outpatients with primary OCD (DSM-IV) recruited between August 2003 and March 2008 from 7 centers of the Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders. The following assessment instruments were used: the Yale-Brown Obsessive Compulsive Scale, the Dimensional Yale-Brown Obsessive Compulsive Scale, the Beck Depression and Anxiety Inventories, the Structured Clinical Interview for DSM-IV Axis I Disorders, and 6 specific questions to investigate suicidality. After univariate analyses, logistic regression analyses were performed to adjust the associations between the dependent and explanatory variables for possible confounders.Results: Thirty-six percent of the patients reported lifetime suicidal thoughts, 20% had made suicidal plans, 11% had already attempted suicide, and 10% presented current suicidal thoughts. In the logistic regression, only lifetime major depressive disorder and posttraumatic stress disorder (PTSD) remained independently associated with all aspects of suicidal behaviors. The sexual/religious dimension and comorbid substance use disorders remained associated with suicidal thoughts and plans, while impulse-control disorders were associated with current suicidal thoughts and with suicide plans and attempts.Conclusions: The risk of suicidal behaviors must be carefully investigated in OCD patients, particularly those with symptoms of the sexual/religious dimension and comorbid major depressive disorder, PTSD, substance use disorders, and impulse-control disorders.J Clin Psychiatry 2011;72(1):17-26Submitted: August 28, 2009; accepted December 14, 2009(doi:10.4088/JCP.09m05651blu).Corresponding author: Albina R. Torres, MD, PhD, Departamento de Neurologia, Psicologia e Psiquiatria, Faculdade de Medicina de Botucatu, University Estadual Paulista (UNESP), Distrito de Rubião Jr, 18618-970, Botucatu, São Paulo, Brazil (torresar@fmb.unesp.br)." @default.
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- W2033492904 date "2011-01-15" @default.
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- W2033492904 title "Suicidality in Obsessive-Compulsive Disorder" @default.
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- W2033492904 doi "https://doi.org/10.4088/jcp.09m05651blu" @default.
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